Name : Cullin 7 Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN3487487363
| Long name | ALEXA FLUOR 488 Conjugated, Cullin 7 Polyclonal Antibody |
| Also known as | Anti-Cullin 7 PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Cullin 7 |
| Specificity | This is a highly specific antibody against Cullin 7 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Cullin 7 |
| Gene ID Number | 9820 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | An autosomal recessive disorder characterized by severe pre- and postnatal growth retardation, In vitro, Probably plays a role in the degradation of proteins involved in endothelial proliferation and/or differentiation (By similarity), Seems not to promote polyubiquitination and proteasomal degradation of TP53, Skeletal changes include long slender tubular bones and tall vertebral bodies, and normal intelligence and endocrine function, complexes of CUL7 with either CUL9 or FBXW8 or TP53 contain E3 ubiquitin-protein ligase activity, facial dysmorphism, large head circumference, which mediates the ubiquitination and subsequent proteasomal degradation of target proteins, Component of a probable SCF-like E3 ubiquitin-protein ligase complex, Involvement in disease: Defects in CUL7 are the cause of 3M syndrome type 1 (3M1) |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | dJ20C7, 5 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Cullin 7 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | Cullin 7 |
| Short name | Cullin 7 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, Cullin 7 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 21024 |
| Gene | CUL7 |
| Long gene name | cullin 7 |
| Synonyms gene | KIAA0076 |
| Synonyms gene name | KIAA0076 |
| Locus | 6p21, 1 |
| Discovery year | 2003-11-21 |
| GenBank acession | BC033647 |
| Entrez gene record | 9820 |
| Pubmed identfication | 12481031 12904573 |
| RefSeq identity | NM_014780 |
| Classification | Cullins |
| Havana BLAST/BLAT | OTTHUMG00000014718 |