| Long name | CX3CR1 Primary Polyclonal Antibody |
| Also known as | CX3CR1 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | CX3CR1 |
| Specificity | This is a highly specific antibody against CX3CR1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 216-230/355 |
| Subcellular location | Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CX3CR1 |
| Gene ID number | 1524 |
| Swiss Prot | P49238 |
| Tested Applications | FCM, IHC-P, WB |
| Recommended dilutions | FCM(1:20-100), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Acts as coreceptor with CD4 for HIV-1 virus envelope protein (in vitro), Isoform 2 and isoform 3 seem to be more potent HIV-1 coreceptors than isoform 1, Receptor for the CX3C chemokine fractalkine and mediates both its adhesive and migratory functions |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | Beta chemokine receptor-like 1, C-X3-C CKR-1, CCRL1, CMK-BRL-1, CMK-BRL1, CMKBRL1, CMKDR1, CX3C chemokine receptor 1, CX3CR1, Fractalkine receptor, G-protein coupled receptor 13, GPR13, GPRV28, V28 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | CX3CR1 |
| Short name | CX3CR1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | chemokine (C-X3-C motif) receptor 1 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | C-X3-C chemokine receptor activity, CCRL1 and CMKBRL1 and CMKDR1 and GPR13 and GPRV28 and V28, CX3CR1 and IDBG-26647 and ENSG00000168329 and 1524, CX3CR1 and IDBG-644403 and ENSBTAG00000002923 and 100124525, Cx3cr1 and IDBG-204952 and ENSMUSG00000052336 and 13051, Plasma membranes, this GO :0002282 and microglial cell activation involved in immune response and biological process this GO :0004896 and cytokine receptor activity and molecular function this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004950 and chemokine receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006935 and chemotaxis and biological process this GO :0006968 and cellular defense response and biological process this GO :0007155 and cell adhesion and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0009611 and response to wounding and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0016032 and viral process and biological process this GO :0016495 and C-X3-C chemokine receptor activity and molecular function this GO :0016525 and negative regulation of angiogenesis and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0021795 and cerebral cortex cell migration and biological process this GO :0030336 and negative regulation of cell migration and biological process this GO :0032809 and neuronal cell body membrane and cellular component this GO :0043005 and neuron projection and cellular component this GO :0045766 and positive regulation of angiogenesis and biological process this GO :0048246 and macrophage chemotaxis and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0070098 and chemokine-mediated signaling pathway and biological process this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0071560 and cellular response to transforming growth factor beta stimulus and biological process this GO :2001240 and negative regulation of extrinsic apoptotic signaling pathway in absence of ligand and biological process, this GO :0004896: cytokine receptor activity, this GO :0004896: cytokine receptor activity and also this GO :0004930: G-protein coupled receptor activity and also this GO :0004950: chemokine receptor activity and also this GO :0005515: protein binding and also this GO :0016495: C-X3-C chemokine receptor activity, this GO :0004930: G-protein coupled receptor activity, this GO :0004950: chemokine receptor activity, this GO :0005515: protein binding, this GO :0016495: C-X3-C chemokine receptor activity, chemokine (C-X3-C motif) receptor 1 |
| Identity | 2558 |
| Gene | CX3CR1 |
| Long gene name | C-X3-C motif chemokine receptor 1 |
| Synonyms gene | GPR13 CMKBRL1 |
| Synonyms gene name | chemokine (C-X3-C) receptor 1 chemokine (C-X3-C motif) receptor 1 |
| Synonyms | CMKDR1 V28 CCRL1 |
| Locus | 3p22, 2 |
| Discovery year | 1998-01-12 |
| GenBank acession | BC028078 |
| Entrez gene record | 1524 |
| Pubmed identfication | 9726990 7646814 |
| RefSeq identity | NM_001337 |
| Classification | C-X-3-C motif chemokine receptors |
| Havana BLAST/BLAT | OTTHUMG00000156249 |
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