Name : CXCR6/BONZO Antibody, ALEXA FLUOR 594
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN3409239644
| Long name | ALEXA FLUOR 594 Conjugated, CXCR6/BONZO Polyclonal Antibody |
| Also known as | Anti-CXCR6/BONZO PAb ALEXA FLUOR 594 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 594, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | CXCR6/BONZO |
| Specificity | This is a highly specific antibody against CXCR6/BONZO |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 141-164/342 |
| Subcellular location | Transmembrane, Helical |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CXCR6 |
| Gene ID Number | 10663 |
| Swiss Prot | O00574 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Bonzo mRNA expression has been localized to lymphoid tissues and activated peripheral blood lymphocytes, During progression of the infection, HIV1 infection relies upon interaction with a chemokine receptor, SIV also utilizes CCR5 in the early stages of infection, They are dependent upon an interaction between the viral envelope glycoprotein with T cell antigen T4 (CD4) and a G protein coupled receptor (GPCR), but during progression it tends to rely on two orphan GPCR's named chemokine (C-X-C) receptor 6 (Bonzo) and G protein coupled receptor 15 (BOB/GRP15), the virus tends to rely upon chemokine (C-X-C) receptor 4 (CXCR4), usually chemokine (C-C) receptor 5 (CCR5), Human Immunodeficiency Virus (HIV) and Simian Immunodeficiency Virus (SIV) require coreceptors to enter and infect target cells |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | TYMSTR STRL33 BONZO CD186 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | 594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated | Alexa conjugate 1 |
| Gene target | CXCR6/BONZO |
| Short name | CXCR6/BONZO Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 594 |
| Alternative name | ALEXA FLUOR 594, chemokine (C-X-C motif) receptor 6/BONZO (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | BONZO and CD186 and STRL33 and TYMSTR, C-X-C chemokine receptor activity, CXCR6 and IDBG-29993 and ENSG00000172215 and 10663, CXCR6 and IDBG-646261 and ENSBTAG00000015708 and 506807, Cxcr6 and IDBG-206490 and ENSMUSG00000048521 and 80901, Plasma membranes, this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006935 and chemotaxis and biological process this GO :0006954 and inflammatory response and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0015026 and coreceptor activity and molecular function this GO :0016021 and integral component of membrane and cellular component this GO :0016494 and C-X-C chemokine receptor activity and molecular function this GO :0019079 and viral genome replication and biological process this GO :0070098 and chemokine-mediated signaling pathway and biological process, this GO :0004930: G-protein coupled receptor activity, this GO :0004930: G-protein coupled receptor activity and also this GO :0015026: coreceptor activity and also this GO :0016494: C-X-C chemokine receptor activity, this GO :0015026: coreceptor activity, this GO :0016494: C-X-C chemokine receptor activity, chemokine (C-X-C motif) receptor 6 |
| Identity | 16647 |
| Gene | CXCR6 |
| Long gene name | C-X-C motif chemokine receptor 6 |
| Synonyms gene name | chemokine (C-X-C motif) receptor 6 |
| Locus | 3p21, 31 |
| Discovery year | 2002-08-23 |
| GenBank acession | AF007545 |
| Entrez gene record | 10663 |
| Pubmed identfication | 9166430 9230441 |
| Classification | CD molecules C-X-C motif chemokine receptors |
| Havana BLAST/BLAT | OTTHUMG00000133448 |