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CYB5R3 Antibody

CYB5R3 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameCYB5R3 Primary Polyclonal Antibody
Also known asCYB5R3 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenCYB5R3
SpecificityThis is a highly specific antibody against CYB5R3
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CYB5R3
Gene ID number1727
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen A serine residue at position 117 seems to only be found in persons of African origin, Asians, CYB5R3 belongs to the flavoprotein pyridine nucleotide cytochrome reductase family and has two naturally occuring isoforms, CYB5R3 is involved in the desaturation and elongation of fatty acids, Defects in CYB5R3 are the cause of hereditary methemoglobinemia (HM), Indo-Aryans or Arabs, Isoform 1 is anchored to the cytoplasmic side of the endoplasmic reticulum membrane and mitochondrion outer membrane, It is not found in Caucasians, The allele frequency is 0, There are three forms of this disease: type 1 (HM1), This difference seems to have no effect on the enzyme activity, Type 2 is a severe form accompanied by mental retardation and neurological impairment, and type 3 (HM3), cholesterol biosynthesis, drug metabolism and, in erythrocytes, in which the enzyme is completely deficient, in which the enzyme is only deficient in erythrocytes with a mild cyanosis, methemoglobin reduction, type 2 (HM2), where the deficiency is seen in all blood cells, while isoform 2 is the soluble form found in erythrocytes, 23 in African Americans, CYB5R3 is a 301 amino acid protein encoded by the human gene CYB5R3
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Cyb5r3, Cytochrome b5 reductase, Cytochrome b5 reductase 3, DIA1, Diaphorase 1, Diaphorase-1, NADH cytochrome b5 reductase 3, NADH-cytochrome b5 reductase 3 membrane-bound form, NADH-cytochrome b5 reductase 3 soluble form, NB5R3_HUMAN, OTTHUMP00000028761, OTTHUMP00000198435, OTTHUMP00000198574, OTTHUMP00000198662, OTTHUMP00000198665, B5R
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetCYB5R3
Short nameCYB5R3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCYB5R3 (Antibody to)
Alternative techniqueantibodies
Identity 2873
Gene CYB5R3
Long gene name cytochrome b5 reductase 3
Synonyms gene DIA1
Synonyms gene name diaphorase (NADH) (cytochrome b-5 reductase)
Synonyms name NADH-cytochrome b5 reductase 3
Locus 22q13, 2
Discovery year 2001-06-22
GenBank acession M16461
Entrez gene record 1727
Pubmed identfication 2479590 3268037
Havana BLAST/BLAT OTTHUMG00000150745

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