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CYB5R3 Antibody, Cy5.5 Conjugated

CYB5R3 Antibody, Cy5.5 Conjugated size: 0.1ml 350

Price 350
Size 0.1ml
Long name Cy5, 5 Conjugated, CYB5R3 Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugation Cy5, 5, 5, Cy5
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCYB5R3
SpecificityThis is a highly specific antibody against CYB5R3
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human CYB5R3
Gene ID number1727
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background A serine residue at position 117 seems to only be found in persons of African origin, Asians, CYB5R3 belongs to the flavoprotein pyridine nucleotide cytochrome reductase family and has two naturally occuring isoforms, CYB5R3 is involved in the desaturation and elongation of fatty acids, Defects in CYB5R3 are the cause of hereditary methemoglobinemia (HM), Indo-Aryans or Arabs, Isoform 1 is anchored to the cytoplasmic side of the endoplasmic reticulum membrane and mitochondrion outer membrane, It is not found in Caucasians, The allele frequency is 0, There are three forms of this disease: type 1 (HM1), This difference seems to have no effect on the enzyme activity, Type 2 is a severe form accompanied by mental retardation and neurological impairment, and type 3 (HM3), cholesterol biosynthesis, drug metabolism and, in erythrocytes, in which the enzyme is completely deficient, in which the enzyme is only deficient in erythrocytes with a mild cyanosis, methemoglobin reduction, type 2 (HM2), where the deficiency is seen in all blood cells, while isoform 2 is the soluble form found in erythrocytes, 23 in African Americans, CYB5R3 is a 301 amino acid protein encoded by the human gene CYB5R3
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission675nm/694nm
Properties Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths
Gene targetCYB5R3 Conjugated
Short name Conjugated, CYB5R3 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label5, Cy5
Alternative name cyanine 5, 5 coupled, CYB5R3 (Antibody to)
Alternative techniqueantibodies
Identity 2873
Gene CYB5R3
Long gene name cytochrome b5 reductase 3
Synonyms gene DIA1
Synonyms gene name diaphorase (NADH) (cytochrome b-5 reductase)
Synonyms name NADH-cytochrome b5 reductase 3
Locus 22q13, 2
Discovery year 2001-06-22
GenBank acession M16461
Entrez gene record 1727
Pubmed identfication 2479590 3268037
Havana BLAST/BLAT OTTHUMG00000150745

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