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Cyclin A2 Antibody / CCNA2

Cyclin A2 Antibody / CCNA2 size: 0.1mg 406

Supplier NJS POLY
Price 406
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenCyclin A2 / CCNA2
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications IHC-P, WB
Recommended dilutions1-0, 5-1ug/ml, 5ug/ml, IHC (Paraffin): 0, Western blot: 0
NotesOptimal dilution of the Cyclin A2 antibody should be determined by the researcher
Intented useThis Cyclin A2 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P20248
PurityAntigen affinity
Description And Cyclin A2 is synthesized at the onset of S phase and localizes to the nucleus, Cyclins function as regulators of CDK kinases, Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event, In contrast to cyclin A1, Phosphorylation of CDC6 and MCM4 by the cyclin A2-CDK2 complex prevents re-replication of DNA during the cell cycle, The protein encoded by this gene belongs to the highly conserved cyclin family, This cyclin binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions, is mapped to 4q27, known as CCNA2, this cyclin is expressed in all tissues tested, where the cyclin A2-CDK2 complex is implicated in the initiation and progression of DNA synthesis, which is present only in germ cells, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle, Cyclin A2
ImmunogenAmino acids 10-168 of human Cyclin A2 were used as the immunogen for the Cyclin A2 antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Cyclin A2 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetCyclin A2 / CCNA2
Short nameCyclin A2 Antibody / CCNA2
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCyclin A2 (Antibody to) / CCNA2
Alternative techniqueantibodies
Identity 1578
Gene CCNA2
Long gene name cyclin A2
Synonyms gene CCNA CCN1
Locus 4q27
Discovery year 1990-04-09
Entrez gene record 890
Pubmed identfication 1675006
RefSeq identity NM_001237
Classification Cyclins
Havana BLAST/BLAT OTTHUMG00000133072

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