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Cyclin C Antibody

Cyclin C Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameCyclin C Primary Polyclonal Antibody
Also known asCyclin C PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenCyclin C
SpecificityThis is a highly specific antibody against Cyclin C
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range1-50/283
Subcellular locationNucleus
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Cyclin C
Gene ID number892
Swiss ProtP24863
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Binds to and activates cyclin-dependent kinase CDK8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery, Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes, which may inhibit the formation of a transcription initiation complex, Component of the Mediator complex
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CCNC, Cyclin-C, SRB11 homolog, hSRB11, CycC
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetCyclin C
Short nameCyclin C Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCyclin C (Antibody to)
Alternative techniqueantibodies
Identity 1581
Gene CCNC
Long gene name cyclin C
Synonyms CycC
Locus 6q16, 2
Discovery year 1991-12-10
Entrez gene record 892
Pubmed identfication 1833066
RefSeq identity NM_005190
Classification Cyclins Mediator complex
Havana BLAST/BLAT OTTHUMG00000015268

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