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Cyclin D1 (AF2G5) Monoclonal Antibody

Cyclin D1 (AF2G5) Monoclonal Antibody size: 0.1ml 362

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 362
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameCyclin D1 (AF2G5) Monoclonal Antibody
Also known asCyclin D1 (AF2G5) Monoclonal Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenCyclin D1
SpecificityThis is a highly specific antibody against Cyclin D1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityMonoclonal
Clone numberAF2G5
SourceRecombinant human protein purified from E, coli (His-Cyclin D1)
Gene ID number595
Swiss ProtP24385
Tested Applications IP, WB
Recommended dilutions000) IP (2 ul), WB (1:1
Cross reactivity Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Also substrate for SMAD3, Component of the ternary complex, Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals, Exhibits transcriptional corepressor activity with INSM1 on the NEUROD1 and INS promoters in a cell cycle-independent manner, Hypophosphorylates RB1 in early G(1) phase, Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase, cyclin D1/CDK4/CDKN1B, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity, required for nuclear translocation and activity of the cyclin D-CDK4 complex, Regulatory component of the cyclin D1-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition
Purification methodAmmonium sulfate precipitation
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names B-cell lymphoma 1 protein, BCL-1, BCL-1 oncogene, CCND1, D11S287E, G1/S-specific cyclin-D1, PRAD1, PRAD1 oncogene, U21B31, BCL1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene targetCyclin D1 (AF2G5) Monoclonal
Short nameCyclin D1 (AF2G5) Monoclonal Antibody
Technique Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative nameCyclin D1 (AF2G5) monoclonal (Antibody to)
Alternative techniqueantibodies

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