Cyclin D2 Antibody, Biotin Conjugated

Cyclin D2 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1

Price 333

Size 0.1ml

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Long name	Biotin Conjugated, Cyclin D2 Polyclonal Antibody
Category	Conjugated Primary Antibodies
Conjugation	Biotinylated
Host Organism	Rabbit (Oryctolagus cuniculus)
Target Antigen	Cyclin D2
Specificity	This is a highly specific antibody against Cyclin D2
Modification	Unmodified
Modification site	None
Clonality	Polyclonal
Clone	Polyclonal antibody
Concentration	1ug per 1ul
Immunogen_range	150-200/288
Subcellular location	Membrane bound, Nucleus, Cytoplasm
Source	KLH conjugated synthetic peptide derived from human Cyclin D2
Gene ID number	894
Swiss Prot	P30279
Tested applications	IHC-P, WB
Recommended dilutions	IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity	Mouse, Rat, Human
Crossreactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background	Also substrate for SMAD3, Component of the ternary complex, Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals, Hypophosphorylates RB1 in early G(1) phase, Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase, cyclin D2/CDK4/CDKN1B, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity, required for nuclear translocation and activity of the cyclin D-CDK4 complex (By similarity), Regulatory component of the cyclin D2-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition
Purification method	This antibody was purified via Protein A
Storage conditions	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission	N/A
Synonyms	CCND2, G1/S-specific cyclin-D2, KIAK2, MPPH3
Properties	Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target	Cyclin D2 Conjugated
Short name	Conjugated, Cyclin D2 Antibody
Technique	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label	Biotin
Alternative name	biotinilated coupled, Cyclin D2 (Antibody to)
Alternative technique	antibodies

Cyclin D2 Antibody, Biotin Conjugated

Cyclin D2 Antibody, Biotin Conjugated size: 0.1ml 333

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