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Cyclin E Antibody

Cyclin E Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameCyclin E Primary Polyclonal Antibody
Also known asCyclin E PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenCyclin E
SpecificityThis is a highly specific antibody against Cyclin E
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range370-411/411
Subcellular locationNucleus
SourceKLH conjugated synthetic peptide derived from rat Cyclin E
Gene ID number25729
Swiss ProtP39949
Tested Applications FCM, IF(IHC-P), IHC-P, WB
Recommended dilutions FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Rat, Mouse
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Cyclins function as regulators of CDK kinases, Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event, Overexpression of this gene has been observed in many tumors, The encoded protein has a 15 aa longer N-terminus, This cyclin forms a complex with and functions as a regulatory subunit of CDK2, This protein accumulates at the G1-S phase boundary and is degraded as cells progress through S phase, This protein was found to associate with, Transcript Variant: This variant (1) contains a different 5' end region, Two additional splice variants were reported but detailed nucleotide sequence information is not yet available, Two alternatively spliced transcript variants of this gene, and be involved in, and thus may contribute to tumorigenesis, as compared to isoform 2, have been described, the phosphorylation of NPAT protein (nuclear protein mapped to the ATM locus), when compared to variant 2, which encode distinct isoforms, which includes an upstream in-frame translation start codon, which participates in cell-cycle regulated histone gene expression and plays a critical role in promoting cell-cycle progression in the absence of pRB, which results in chromosome instability, whose activity is required for cell cycle G1/S transition, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle, The protein encoded by this gene belongs to the highly conserved cyclin family
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CYCLE, Ccne1, G1/S-specific cyclin-E1, Ccne
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetCyclin E
Short nameCyclin E Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCyclin E (Antibody to)
Alternative techniqueantibodies

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