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Cyclin E Antibody, ALEXA FLUOR 594

Cyclin E Antibody, ALEXA FLUOR 594 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 594 Conjugated, Cyclin E Polyclonal Antibody
Also known asAnti-Cyclin E PAb ALEXA FLUOR 594
CategoryConjugated Primary Antibodies
Conjugated with 594, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCyclin E
SpecificityThis is a highly specific antibody against Cyclin E
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range370-411/411
Subcellular locationNucleus
SourceKLH conjugated synthetic peptide derived from rat Cyclin E
Gene ID Number25729
Swiss ProtP39949
Tested applications IF(IHC-P), FCM
Recommended dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
Crossreactivity Rat, Mouse
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Cyclins function as regulators of CDK kinases, Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event, Overexpression of this gene has been observed in many tumors, The encoded protein has a 15 aa longer N-terminus, This cyclin forms a complex with and functions as a regulatory subunit of CDK2, This protein accumulates at the G1-S phase boundary and is degraded as cells progress through S phase, This protein was found to associate with, Transcript Variant: This variant (1) contains a different 5' end region, Two additional splice variants were reported but detailed nucleotide sequence information is not yet available, Two alternatively spliced transcript variants of this gene, and be involved in, and thus may contribute to tumorigenesis, as compared to isoform 2, have been described, the phosphorylation of NPAT protein (nuclear protein mapped to the ATM locus), when compared to variant 2, which encode distinct isoforms, which includes an upstream in-frame translation start codon, which participates in cell-cycle regulated histone gene expression and plays a critical role in promoting cell-cycle progression in the absence of pRB, which results in chromosome instability, whose activity is required for cell cycle G1/S transition, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle, The protein encoded by this gene belongs to the highly conserved cyclin family
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission590nm/617nm
Synonyms CYCLE, Ccne1, G1/S-specific cyclin-E1, Ccne
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation 594, ALEXA FLUOR®, Alexa Fluor
ConjugatedAlexa conjugate 1
Gene targetCyclin E
Short nameCyclin E Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 594
Alternative name ALEXA FLUOR 594, Cyclin E (Antibody to)
Alternative techniqueantibodies

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