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CYLD (Ser418) Antibody

CYLD (Ser418) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameCYLD (Ser418) Primary Polyclonal Antibody
Also known asCYLD (Ser418) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenCYLD Ser418
Specificity This phophorylation site is homologous to that of Ser414 in Mouse and Ser415 in Rat, This is a highly specific antibody against CYLD Ser418
Modification(s)Phosphorylation
Modification site(s)Ser418
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range390-440/956
Subcellular location Cell membrane, Cytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from human CYLD around the phosphorylation site of Ser418
Gene ID number1540
Swiss ProtQ9NQC7
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Contributes to the regulation of cell survival, Dispensable for the maturation of intrathymic natural killer cells, Has endodeubiquitinase activity, Inhibits HDAC6 and thereby promotes acetylation of alpha-tubulin and stabilization of microtubules, Inhibits nuclear translocation of NF-kappa-B, Negative regulator of Wnt signaling, Negatively regulates TNFRSF11A signaling and osteoclastogenesis (By similarity), Plays a role in the regulation of inflammation and the innate immune response, Plays a role in the regulation of microtubule dynamics, Plays an important role in the regulation of pathways leading to NF-kappa-B activation, Required for normal cell cycle progress and normal cytokinesis, and angiogenesis, and thereby contributes to the regulation of cell proliferation, but required for the continued survival of immature natural killer cells, cell migration, cell polarization, proliferation and differentiation via its effects on NF-kappa-B activation, via its effects on NF-kappa-B activation, Protease that specifically cleaves 'Lys-63'-linked polyubiquitin chains
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names BRSS, CDMT, CYLD, CYLD1, CYLDI, Deubiquitinating enzyme CYLD, HSPC057, KIAA0849, MFT, MFT1, SBS, TEM, USPL2, Ubiquitin carboxyl-terminal hydrolase CYLD, Ubiquitin thioesterase CYLD, Ubiquitin-specific-processing protease CYLD, EAC
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetCYLD (Ser418)
Short nameCYLD (Ser418) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCYLD (Ser418) (Antibody to)
Alternative techniqueantibodies
Identity 2584
Gene CYLD
Long gene name CYLD lysine 63 deubiquitinase
Synonyms gene CYLD1
Synonyms gene name cylindromatosis (turban tumor syndrome)
Synonyms KIAA0849 USPL2
Synonyms name ubiquitin specific peptidase like 2
Locus 16q12, 1
Discovery year 1996-12-17
GenBank acession AB020656
Entrez gene record 1540
Pubmed identfication 7493027
Classification Ubiquitin specific peptidases
Havana BLAST/BLAT OTTHUMG00000173404
Locus Specific Databases LRG_491

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