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CYP1A2 Antibody

CYP1A2 Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenCYP1A2
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, IF, IHC, WB
Recommended dilutionsIHC (Paraffin): 1:10-1:50, Immunofluorescence: 1:10-1:50, Western blot: 1:1000
NotesTitration of the CYP1A2 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis CYP1A2 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P05177
PurityAntigen affinity
Description Also acts in the metabolism of aflatoxin B1 and acetaminophen, CYP1A2 is involved in an NADPH-dependent electron transport pathway, Caffeine is metabolized primarily by cytochrome CYP1A2 in the liver through an initial N3-demethylation, Catalizes the N-hydroxylation of heterocyclic amines and the O-deethylation of phenacetin, In liver microsomes, It oxidizes a variety of structurally unrelated compounds, Most active in catalyzing 2-hydroxylation, Participates in the bioactivation of carcinogenic aromatic and heterocyclic amines, [UniProt], and xenobiotics, fatty acids, including steroids, Cytochromes P450 are a group of heme-thiolate monooxygenases
ImmunogenA portion of amino acids 255-282 from the human protein was used as the immunogen for this CYP1A2 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the CYP1A2 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetCYP1A2
Short nameCYP1A2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCYP1A2 (Antibody to)
Alternative techniqueantibodies
Identity 2596
Gene CYP1A2
Long gene name cytochrome P450 family 1 subfamily A member 2
Synonyms gene name cytochrome P450, family 1, polypeptide 2 , polypeptide 2 cytochrome P450, subfamily A, subfamily I (aromatic compound-inducible)
Synonyms P3-450 CP12
Locus 15q24, 1
Discovery year 1990-04-25
GenBank acession AF182274
Entrez gene record 1544
Pubmed identfication 15128046
RefSeq identity NM_000761
Classification Cytochrome P450 family 1
Havana BLAST/BLAT OTTHUMG00000172901
Locus Specific Databases Human Cytochrome P450 (CYP) Allele Nomenclature Committee

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