Name : CYP1B1 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN7815341505
| Long name | CYP1B1 Primary Polyclonal Antibody |
| Also known as | CYP1B1 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | CYP1B1 |
| Specificity | This is a highly specific antibody against CYP1B1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 450-485/543 |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CYP1B1 |
| Gene ID number | 1545 |
| Swiss Prot | Q16678 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Contributes to oxidative homeostasis and ultrastructural organization and function of trabecular meshwork tissue through modulation of POSTN expression, In liver microsomes, It oxidizes a variety of structurally unrelated compounds, Plays an important role in the regulation of perivascular cell proliferation, Preferentially oxidizes 17beta-estradiol to the carcinogenic 4-hydroxy derivative, Promotes angiogenesis by removing cellular oxygenation products, These changes are concommitant with the endothelial nitric oxide synthase activity and nitric oxide synthesis, and a variety of procarcinogenic compounds to their activated forms, and survival through modulation of the intracellular oxidative state and NF-kappa-B expression and/or activity, cell adhesion and capillary morphogenesis, during angiogenesis, fatty acids, including polycyclic aromatic hydrocarbons, including steroids, migration, release of antiangiogenic factor THBS2, retinoid and xenobiotics, then allowing endothelial cells migration, thereby decreasing oxidative stress, this enzyme is involved in an NADPH-dependent electron transport pathway, Cytochromes P450 are a group of heme-thiolate monooxygenases |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | CYP1B1, CYPIB1, Cytochrome P450 1B1, GLC3A, P4501B1, CP1B |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | CYP1B1 |
| Short name | CYP1B1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | CYP1B1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 2597 |
| Gene | CYP1B1 |
| Long gene name | cytochrome P450 family 1 subfamily B member 1 |
| Synonyms gene | GLC3A |
| Synonyms gene name | cytochrome P450, family 1, polypeptide 1 , polypeptide 1 (glaucoma 3, primary infantile) cytochrome P450, subfamily B, subfamily I (dioxin-inducible) |
| Synonyms | CP1B |
| Locus | 2p22, 2 |
| Discovery year | 1994-12-20 |
| GenBank acession | U56438 |
| Entrez gene record | 1545 |
| Pubmed identfication | 8175734 15128046 |
| RefSeq identity | NM_000104 |
| Classification | Cytochrome P450 family 1 |
| Havana BLAST/BLAT | OTTHUMG00000100970 |
| Locus Specific Databases | Human Cytochrome P450 (CYP)Allele Nomenclature Committee |