Name : CYP1B1 Antibody, FITC Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN7714769874
| Long name | FITC Conjugated, CYP1B1 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | CYP1B1 |
| Specificity | This is a highly specific antibody against CYP1B1 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen_range | 450-485/543 |
| Source | KLH conjugated synthetic peptide derived from human CYP1B1 |
| Gene ID number | 1545 |
| Swiss Prot | Q16678 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Contributes to oxidative homeostasis and ultrastructural organization and function of trabecular meshwork tissue through modulation of POSTN expression, In liver microsomes, It oxidizes a variety of structurally unrelated compounds, Plays an important role in the regulation of perivascular cell proliferation, Preferentially oxidizes 17beta-estradiol to the carcinogenic 4-hydroxy derivative, Promotes angiogenesis by removing cellular oxygenation products, These changes are concommitant with the endothelial nitric oxide synthase activity and nitric oxide synthesis, and a variety of procarcinogenic compounds to their activated forms, and survival through modulation of the intracellular oxidative state and NF-kappa-B expression and/or activity, cell adhesion and capillary morphogenesis, during angiogenesis, fatty acids, including polycyclic aromatic hydrocarbons, including steroids, migration, release of antiangiogenic factor THBS2, retinoid and xenobiotics, then allowing endothelial cells migration, thereby decreasing oxidative stress, this enzyme is involved in an NADPH-dependent electron transport pathway, Cytochromes P450 are a group of heme-thiolate monooxygenases |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Synonyms | CP1B |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | CYP1B1 Conjugated |
| Short name | FITC Conjugated, CYP1B1 Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | FITC |
| Alternative name | fluorecein coupled, CYP1B1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 2597 |
| Gene | CYP1B1 |
| Long gene name | cytochrome P450 family 1 subfamily B member 1 |
| Synonyms gene | GLC3A |
| Synonyms gene name | cytochrome P450, family 1, polypeptide 1 , polypeptide 1 (glaucoma 3, primary infantile) cytochrome P450, subfamily B, subfamily I (dioxin-inducible) |
| Locus | 2p22, 2 |
| Discovery year | 1994-12-20 |
| GenBank acession | U56438 |
| Entrez gene record | 1545 |
| Pubmed identfication | 8175734 15128046 |
| RefSeq identity | NM_000104 |
| Classification | Cytochrome P450 family 1 |
| Havana BLAST/BLAT | OTTHUMG00000100970 |
| Locus Specific Databases | Human Cytochrome P450 (CYP)Allele Nomenclature Committee |