Name : CYP21 Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN9275864485
| Long name | ALEXA FLUOR 488 Conjugated, CYP21 Polyclonal Antibody |
| Also known as | Anti-CYP21 PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | CYP21 |
| Specificity | This is a highly specific antibody against CYP21 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 130-180/494 |
| Subcellular location | Cell membrane, Membrane bound |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CYP21 |
| Gene ID Number | 1589 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | A related pseudogene is located near this gene, Its activity is required for the synthesis of steroid hormones including cortisol and aldosterone, Mutations in this gene cause congenital adrenal hyperplasia, The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, This protein localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position, Two transcript variants encoding different isoforms have been found for this gene, [provided by RefSeq], gene conversion events involving the functional gene and the pseudogene are thought to account for many cases of steroid 21-hydroxylase deficiency, steroids and other lipids, This gene encodes a member of the cytochrome P450 superfamily of enzymes |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | P450c21B CA21H CPS1 CAH1 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the CYP21 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | CYP21 |
| Short name | CYP21 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, CYP21 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 2600 |
| Gene | CYP21A2 |
| Long gene name | cytochrome P450 family 21 subfamily A member 2 |
| Synonyms gene | CYP21 CYP21B |
| Synonyms gene name | congenital adrenal hyperplasia), cytochrome P450, family 21, polypeptide 2 , polypeptide 2 cytochrome P450, subfamily A, subfamily XXIA (steroid 21-hydroxylase |
| Synonyms name | Steroid 21-monooxygenase |
| Locus | 6p21, 33 |
| Discovery year | 1986-01-01 |
| GenBank acession | X58906 |
| Entrez gene record | 1589 |
| RefSeq identity | NM_000500 |
| Classification | Cytochrome P450 family 21 |
| Havana BLAST/BLAT | OTTHUMG00000031069 |
| Locus Specific Databases | Human Cytochrome P450 (CYP) Allele Nomenclature Committee LRG_829 |