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CYP21 Antibody, Biotin Conjugated

CYP21 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, CYP21 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCYP21
SpecificityThis is a highly specific antibody against CYP21
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range130-180/494
Subcellular location Cell membrane, Membrane bound
SourceKLH conjugated synthetic peptide derived from human CYP21
Gene ID number1589
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background A related pseudogene is located near this gene, Its activity is required for the synthesis of steroid hormones including cortisol and aldosterone, Mutations in this gene cause congenital adrenal hyperplasia, The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, This protein localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position, Two transcript variants encoding different isoforms have been found for this gene, [provided by RefSeq], gene conversion events involving the functional gene and the pseudogene are thought to account for many cases of steroid 21-hydroxylase deficiency, steroids and other lipids, This gene encodes a member of the cytochrome P450 superfamily of enzymes
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms P450c21B CA21H CPS1 CAH1
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetCYP21 Conjugated
Short name Conjugated, CYP21 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, CYP21 (Antibody to)
Alternative techniqueantibodies
Identity 2600
Gene CYP21A2
Long gene name cytochrome P450 family 21 subfamily A member 2
Synonyms gene CYP21 CYP21B
Synonyms gene name congenital adrenal hyperplasia), cytochrome P450, family 21, polypeptide 2 , polypeptide 2 cytochrome P450, subfamily A, subfamily XXIA (steroid 21-hydroxylase
Synonyms name Steroid 21-monooxygenase
Locus 6p21, 33
Discovery year 1986-01-01
GenBank acession X58906
Entrez gene record 1589
RefSeq identity NM_000500
Classification Cytochrome P450 family 21
Havana BLAST/BLAT OTTHUMG00000031069
Locus Specific Databases Human Cytochrome P450 (CYP) Allele Nomenclature Committee LRG_829

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