| Long name | CYP26A1 Primary Polyclonal Antibody |
| Also known as | CYP26A1 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | CYP26A1 |
| Specificity | This is a highly specific antibody against CYP26A1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CYP26A1 |
| Gene ID number | 1592 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | CYP26A1 is a major retinoic acid catabolic enzyme, CYP26A1 is upregulated in adenomatous polyposis coli mouse adenomas, CYP26A1 plays an important role in protecting tailbud tissues from inappropriate exposure to retinoic acid, CYP26A1 transcription is epigenetically regulated by nuclear retinoic acid receptor â, Mutations in the gene encoding for CYP26A1 are associated with caudal agenesis and spina bifida, P450 enzymes are classified into subfamilies based on their sequence similarities, agenesis of the caudal portions of the digestive and urogenital tracts, and in the intestine of adenomatous polyposis coli (apcmcr) mutant zebrafish embryos, and malformed lumbosacral skeletal elements, and other lipids, human FAP adenomas, human sporadic colon carcinomas, imperforate anus, steroids, &circ, «, 2, The cytochrome P450 proteins (CYPs) are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | CP26A_HUMAN, CYP26, CYP26A 1, Cytochrome P450 26A1, Cytochrome P450 family 26 subfamily A polypeptide 1, Cytochrome P450 retinoic acid-inactivating 1, Cytochrome P450RAI, OTTHUMP00000020102, OTTHUMP00000020103, P450, P450 retinoic acid inactivating 1, P450RAI, P450RAI1, Retinoic acid 4 hydroxylase, Retinoic acid 4-hydroxylase, Retinoic acid metabolizing cytochrome, Retinoic acid-metabolizing cytochrome, cyp26a1, cytochrome P450, cytochrome P450, family 26, hP450RAI, polypeptide 1, polypeptide 1, subfamily A, subfamily XXVIA, CP26 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | CYP26A1 |
| Short name | CYP26A1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | family 26, polypeptide 1 (Antibody to), subfamily A, cytochrome P450 |
| Alternative technique | antibodies |
| Alternative to gene target | CP26 and CYP26 and P450RAI and P450RAI1, CYP26A1 and IDBG-637647 and ENSBTAG00000021118 and 539047, CYP26A1 and IDBG-82645 and ENSG00000095596 and 1592, Cyp26a1 and IDBG-162003 and ENSMUSG00000024987 and 13082, Cytoplasm, acting on paired donors, acting on paired donors, acting on paired donors, family 26, oxidoreductase activity, polypeptide 1, subfamily A, this GO :0001972 and retinoic acid binding and molecular function this GO :0005506 and iron ion binding and molecular function this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0006766 and vitamin metabolic process and biological process this GO :0006805 and xenobiotic metabolic process and biological process this GO :0007417 and central nervous system development and biological process this GO :0008152 and metabolic process and biological process this GO :0008401 and retinoic acid 4-hydroxylase activity and molecular function this GO :0009952 and anterior/posterior pattern specification and biological process this GO :0014032 and neural crest cell development and biological process this GO :0016705 and oxidoreductase activity, this GO :0001972: retinoic acid binding, this GO :0001972: retinoic acid binding and also this GO :0005506: iron ion binding and also this GO :0008401: retinoic acid 4-hydroxylase activity and also this GO :0016705: oxidoreductase activity, this GO :0005506: iron ion binding, this GO :0008401: retinoic acid 4-hydroxylase activity, this GO :0016705: oxidoreductase activity, this GO :0019825: oxygen binding, this GO :0020037: heme binding, with incorporation or reduction of molecular oxygen, with incorporation or reduction of molecular oxygen and also this GO :0019825: oxygen binding and also this GO :0020037: heme binding, with incorporation or reduction of molecular oxygen and molecular function this GO :0019825 and oxygen binding and molecular function this GO :0020037 and heme binding and molecular function this GO :0034653 and retinoic acid catabolic process and biological process this GO :0042573 and retinoic acid metabolic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0048384 and retinoic acid receptor signaling pathway and biological process this GO :0048387 and negative regulation of retinoic acid receptor signaling pathway and biological process this GO :0055114 and oxidation-reduction process and biological process this GO :0071300 and cellular response to retinoic acid and biological process, cytochrome P450 |
| Identity | 2603 |
| Gene | CYP26A1 |
| Long gene name | cytochrome P450 family 26 subfamily A member 1 |
| Synonyms gene name | cytochrome P450, family 26, polypeptide 1 , polypeptide 1 cytochrome P450, subfamily A, subfamily XXVIA |
| Synonyms | P450RAI CP26 CYP26 P450RAI1 |
| Locus | 10q23, 33 |
| Discovery year | 1996-12-12 |
| GenBank acession | AF005418 |
| Entrez gene record | 1592 |
| Pubmed identfication | 9228017 9521883 |
| Classification | Cytochrome P450 family 26 |
| Havana BLAST/BLAT | OTTHUMG00000018765 |
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