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CYP26A1 Antibody, FITC Conjugated

CYP26A1 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, CYP26A1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCYP26A1
SpecificityThis is a highly specific antibody against CYP26A1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human CYP26A1
Gene ID number1592
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background CYP26A1 is a major retinoic acid catabolic enzyme, CYP26A1 is upregulated in adenomatous polyposis coli mouse adenomas, CYP26A1 plays an important role in protecting tailbud tissues from inappropriate exposure to retinoic acid, CYP26A1 transcription is epigenetically regulated by nuclear retinoic acid receptor â, Mutations in the gene encoding for CYP26A1 are associated with caudal agenesis and spina bifida, P450 enzymes are classified into subfamilies based on their sequence similarities, agenesis of the caudal portions of the digestive and urogenital tracts, and in the intestine of adenomatous polyposis coli (apcmcr) mutant zebrafish embryos, and malformed lumbosacral skeletal elements, and other lipids, human FAP adenomas, human sporadic colon carcinomas, imperforate anus, steroids, &circ, «, 2, The cytochrome P450 proteins (CYPs) are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms P450RAI CP26 CYP26 P450RAI1
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetCYP26A1 Conjugated
Short name FITC Conjugated, CYP26A1 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name family 26, fluorecein coupled, polypeptide 1 (Antibody to), subfamily A, cytochrome P450
Alternative techniqueantibodies
Alternative to gene target CP26 and CYP26 and P450RAI and P450RAI1, CYP26A1 and IDBG-637647 and ENSBTAG00000021118 and 539047, CYP26A1 and IDBG-82645 and ENSG00000095596 and 1592, Cyp26a1 and IDBG-162003 and ENSMUSG00000024987 and 13082, Cytoplasm, acting on paired donors, acting on paired donors, acting on paired donors, family 26, oxidoreductase activity, polypeptide 1, subfamily A, this GO :0001972 and retinoic acid binding and molecular function this GO :0005506 and iron ion binding and molecular function this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0006766 and vitamin metabolic process and biological process this GO :0006805 and xenobiotic metabolic process and biological process this GO :0007417 and central nervous system development and biological process this GO :0008152 and metabolic process and biological process this GO :0008401 and retinoic acid 4-hydroxylase activity and molecular function this GO :0009952 and anterior/posterior pattern specification and biological process this GO :0014032 and neural crest cell development and biological process this GO :0016705 and oxidoreductase activity, this GO :0001972: retinoic acid binding, this GO :0001972: retinoic acid binding and also this GO :0005506: iron ion binding and also this GO :0008401: retinoic acid 4-hydroxylase activity and also this GO :0016705: oxidoreductase activity, this GO :0005506: iron ion binding, this GO :0008401: retinoic acid 4-hydroxylase activity, this GO :0016705: oxidoreductase activity, this GO :0019825: oxygen binding, this GO :0020037: heme binding, with incorporation or reduction of molecular oxygen, with incorporation or reduction of molecular oxygen and also this GO :0019825: oxygen binding and also this GO :0020037: heme binding, with incorporation or reduction of molecular oxygen and molecular function this GO :0019825 and oxygen binding and molecular function this GO :0020037 and heme binding and molecular function this GO :0034653 and retinoic acid catabolic process and biological process this GO :0042573 and retinoic acid metabolic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0048384 and retinoic acid receptor signaling pathway and biological process this GO :0048387 and negative regulation of retinoic acid receptor signaling pathway and biological process this GO :0055114 and oxidation-reduction process and biological process this GO :0071300 and cellular response to retinoic acid and biological process, cytochrome P450
Identity 2603
Gene CYP26A1
Long gene name cytochrome P450 family 26 subfamily A member 1
Synonyms gene name cytochrome P450, family 26, polypeptide 1 , polypeptide 1 cytochrome P450, subfamily A, subfamily XXVIA
Locus 10q23, 33
Discovery year 1996-12-12
GenBank acession AF005418
Entrez gene record 1592
Pubmed identfication 9228017 9521883
Classification Cytochrome P450 family 26
Havana BLAST/BLAT OTTHUMG00000018765

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