Name : CYP2R1 Antibody, ALEXA FLUOR 594
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN8455133191
| Long name | ALEXA FLUOR 594 Conjugated, CYP2R1 Polyclonal Antibody |
| Also known as | Anti-CYP2R1 PAb ALEXA FLUOR 594 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 594, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | CYP2R1 |
| Specificity | This is a highly specific antibody against CYP2R1 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CYP2R1 |
| Gene ID Number | 120227 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | First described in patients who had rickets at a young age despite a history of adequate vitamin D intake, The cytochrome P450 proteins are mono-oxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, The patients sera had low calcium concentrations, This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor, also known as pseudovitamin D(3) deficiency rickets due to 25-hydroxylase deficiency, elevated alkaline phosphatase activity and low levels of 25-hydroxyvitamin D, low phosphate concentrations, steroids and other lipids, CYP2R1 is a member of the cytochrome P450 superfamily of enzymes, Defects in CYP2R1 are a cause of 25-hydroxyvitamin D(3) deficiency |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 590nm/617nm |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | 594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated | Alexa conjugate 1 |
| Gene target | CYP2R1 |
| Short name | CYP2R1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 594 |
| Alternative name | ALEXA FLUOR 594, CYP2R1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 20580 |
| Gene | CYP2R1 |
| Long gene name | cytochrome P450 family 2 subfamily R member 1 |
| Synonyms gene name | cytochrome P450, family 2, polypeptide 1 , subfamily R |
| Locus | 11p15, 2 |
| Discovery year | 2004-03-11 |
| GenBank acession | AY323817 |
| Entrez gene record | 120227 |
| Pubmed identfication | 12464240 12867411 |
| RefSeq identity | NM_024514 |
| Classification | Cytochrome P450 family 2 |
| Havana BLAST/BLAT | OTTHUMG00000165900 |
| Locus Specific Databases | Human Cytochrome P450 (CYP) Allele Nomenclature Committee |