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CYP2R1 Antibody, Biotin Conjugated

CYP2R1 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, CYP2R1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCYP2R1
SpecificityThis is a highly specific antibody against CYP2R1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human CYP2R1
Gene ID number120227
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background First described in patients who had rickets at a young age despite a history of adequate vitamin D intake, The cytochrome P450 proteins are mono-oxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, The patients sera had low calcium concentrations, This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor, also known as pseudovitamin D(3) deficiency rickets due to 25-hydroxylase deficiency, elevated alkaline phosphatase activity and low levels of 25-hydroxyvitamin D, low phosphate concentrations, steroids and other lipids, CYP2R1 is a member of the cytochrome P450 superfamily of enzymes, Defects in CYP2R1 are a cause of 25-hydroxyvitamin D(3) deficiency
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetCYP2R1 Conjugated
Short name Conjugated, CYP2R1 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, CYP2R1 (Antibody to)
Alternative techniqueantibodies
Identity 20580
Gene CYP2R1
Long gene name cytochrome P450 family 2 subfamily R member 1
Synonyms gene name cytochrome P450, family 2, polypeptide 1 , subfamily R
Locus 11p15, 2
Discovery year 2004-03-11
GenBank acession AY323817
Entrez gene record 120227
Pubmed identfication 12464240 12867411
RefSeq identity NM_024514
Classification Cytochrome P450 family 2
Havana BLAST/BLAT OTTHUMG00000165900
Locus Specific Databases Human Cytochrome P450 (CYP) Allele Nomenclature Committee

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