Name : CYP2R1 Antibody, Cy5.5 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN2259097618
| Long name | Cy5, 5 Conjugated, CYP2R1 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Cy5, 5, 5, Cy5 |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | CYP2R1 |
| Specificity | This is a highly specific antibody against CYP2R1 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human CYP2R1 |
| Gene ID number | 120227 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | First described in patients who had rickets at a young age despite a history of adequate vitamin D intake, The cytochrome P450 proteins are mono-oxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, The patients sera had low calcium concentrations, This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor, also known as pseudovitamin D(3) deficiency rickets due to 25-hydroxylase deficiency, elevated alkaline phosphatase activity and low levels of 25-hydroxyvitamin D, low phosphate concentrations, steroids and other lipids, CYP2R1 is a member of the cytochrome P450 superfamily of enzymes, Defects in CYP2R1 are a cause of 25-hydroxyvitamin D(3) deficiency |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 675nm/694nm |
| Properties | Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated | These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target | CYP2R1 Conjugated |
| Short name | Conjugated, CYP2R1 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | 5, Cy5 |
| Alternative name | cyanine 5, 5 coupled, CYP2R1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 20580 |
| Gene | CYP2R1 |
| Long gene name | cytochrome P450 family 2 subfamily R member 1 |
| Synonyms gene name | cytochrome P450, family 2, polypeptide 1 , subfamily R |
| Locus | 11p15, 2 |
| Discovery year | 2004-03-11 |
| GenBank acession | AY323817 |
| Entrez gene record | 120227 |
| Pubmed identfication | 12464240 12867411 |
| RefSeq identity | NM_024514 |
| Classification | Cytochrome P450 family 2 |
| Havana BLAST/BLAT | OTTHUMG00000165900 |
| Locus Specific Databases | Human Cytochrome P450 (CYP) Allele Nomenclature Committee |