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CYP2R1 Antibody, FITC Conjugated

CYP2R1 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, CYP2R1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCYP2R1
SpecificityThis is a highly specific antibody against CYP2R1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human CYP2R1
Gene ID number120227
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background First described in patients who had rickets at a young age despite a history of adequate vitamin D intake, The cytochrome P450 proteins are mono-oxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, The patients sera had low calcium concentrations, This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor, also known as pseudovitamin D(3) deficiency rickets due to 25-hydroxylase deficiency, elevated alkaline phosphatase activity and low levels of 25-hydroxyvitamin D, low phosphate concentrations, steroids and other lipids, CYP2R1 is a member of the cytochrome P450 superfamily of enzymes, Defects in CYP2R1 are a cause of 25-hydroxyvitamin D(3) deficiency
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetCYP2R1 Conjugated
Short name FITC Conjugated, CYP2R1 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, CYP2R1 (Antibody to)
Alternative techniqueantibodies
Identity 20580
Gene CYP2R1
Long gene name cytochrome P450 family 2 subfamily R member 1
Synonyms gene name cytochrome P450, family 2, polypeptide 1 , subfamily R
Locus 11p15, 2
Discovery year 2004-03-11
GenBank acession AY323817
Entrez gene record 120227
Pubmed identfication 12464240 12867411
RefSeq identity NM_024514
Classification Cytochrome P450 family 2
Havana BLAST/BLAT OTTHUMG00000165900
Locus Specific Databases Human Cytochrome P450 (CYP) Allele Nomenclature Committee

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