Name : CYP46 Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN8431642839
| Long name | Biotin Conjugated, CYP46 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | CYP46 |
| Specificity | This is a highly specific antibody against CYP46 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human CYP46 |
| Gene ID number | 10858 |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, This endoplasmic reticulum protein is expressed exclusively in the brain, producing a product that is more soluble than cholesterol and able to be exported from the brain, steroids and other lipids, where it converts cholesterol to 24S-hydroxycholesterol by adding a hydroxyl group to cholesterol, Cyp46 is also known as 24S-cholesterol hydroxylase, The Cyp46 gene encodes a member of the cytochrome P450 superfamily of enzymes |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | CYP46 Conjugated |
| Short name | Conjugated, CYP46 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, CYP46 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 2641 |
| Gene | CYP46A1 |
| Long gene name | cytochrome P450 family 46 subfamily A member 1 |
| Synonyms gene | CYP46 |
| Synonyms gene name | cytochrome P450, family 46, polypeptide 1 , subfamily 46 (cholesterol 24-hydroxylase) cytochrome P450, subfamily A |
| Locus | 14q32, 2 |
| Discovery year | 1999-08-20 |
| GenBank acession | AF094480 |
| Entrez gene record | 10858 |
| Pubmed identfication | 10377398 |
| Classification | Cytochrome P450 family 46 |
| Havana BLAST/BLAT | OTTHUMG00000171510 |