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CYP46 Antibody, FITC Conjugated

CYP46 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, CYP46 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCYP46
SpecificityThis is a highly specific antibody against CYP46
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human CYP46
Gene ID number10858
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, This endoplasmic reticulum protein is expressed exclusively in the brain, producing a product that is more soluble than cholesterol and able to be exported from the brain, steroids and other lipids, where it converts cholesterol to 24S-hydroxycholesterol by adding a hydroxyl group to cholesterol, Cyp46 is also known as 24S-cholesterol hydroxylase, The Cyp46 gene encodes a member of the cytochrome P450 superfamily of enzymes
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetCYP46 Conjugated
Short name FITC Conjugated, CYP46 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, CYP46 (Antibody to)
Alternative techniqueantibodies
Identity 2641
Gene CYP46A1
Long gene name cytochrome P450 family 46 subfamily A member 1
Synonyms gene CYP46
Synonyms gene name cytochrome P450, family 46, polypeptide 1 , subfamily 46 (cholesterol 24-hydroxylase) cytochrome P450, subfamily A
Locus 14q32, 2
Discovery year 1999-08-20
GenBank acession AF094480
Entrez gene record 10858
Pubmed identfication 10377398
Classification Cytochrome P450 family 46
Havana BLAST/BLAT OTTHUMG00000171510

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