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Cyr61 Antibody

Cyr61 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameCyr61 Primary Polyclonal Antibody
Also known asCyr61 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenCyr61
SpecificityThis is a highly specific antibody against Cyr61
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range250-300/381
Subcellular locationSecreted
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Cyr61
Gene ID number3491
Swiss ProtO00622
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Appears to play a role in wound healing by up-regulating, CYR61-mediated gene regulation is dependent on heparin-binding, Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1, MMP1, MMP3, PAI-1 and integrins alpha-3 and alpha-5, Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, TIMP1, VEGA-C, angiogenesis and cell adhesion, cell migration through integrin alpha-v/beta-5 and cell proliferation through integrin alpha-v/beta-3, chemotaxis, in skin fibroblasts, inflammation and matrix remodeling including VEGA-A, the expression of a number of genes involved in angiogenesis, uPA, Promotes cell proliferation
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CCN family member 1, CYR61, Cysteine-rich angiogenic inducer 61, GIG1, IBP-10, IGF-binding protein 10, IGFBP-10, IGFBP10, Insulin-like growth factor-binding protein 10, Protein CYR61, Protein GIG1, CCN1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetCyr61
Short nameCyr61 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name 61 (Antibody to), angiogenic inducer, cysteine-rich
Alternative techniqueantibodies
Identity 2654
Gene CYR61
Long gene name cysteine rich angiogenic inducer 61
Synonyms gene IGFBP10
Synonyms gene name 61 , angiogenic inducer, cysteine-rich
Synonyms GIG1 CCN1
Locus 1p22, 3
Discovery year 1998-03-02
GenBank acession AF031385
Entrez gene record 3491
Pubmed identfication 9135077
RefSeq identity NM_001554
Classification CYR61/CTGF/NOV matricellular proteins
Havana BLAST/BLAT OTTHUMG00000010577

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