Name : Cyr61 Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN2276382474
| Long name | ALEXA FLUOR 488 Conjugated, Cyr61 Polyclonal Antibody |
| Also known as | Anti-Cyr61 PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Cyr61 |
| Specificity | This is a highly specific antibody against Cyr61 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 250-300/381 |
| Subcellular location | Secreted |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Cyr61 |
| Gene ID Number | 3491 |
| Swiss Prot | O00622 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Appears to play a role in wound healing by up-regulating, CYR61-mediated gene regulation is dependent on heparin-binding, Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1, MMP1, MMP3, PAI-1 and integrins alpha-3 and alpha-5, Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, TIMP1, VEGA-C, angiogenesis and cell adhesion, cell migration through integrin alpha-v/beta-5 and cell proliferation through integrin alpha-v/beta-3, chemotaxis, in skin fibroblasts, inflammation and matrix remodeling including VEGA-A, the expression of a number of genes involved in angiogenesis, uPA, Promotes cell proliferation |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | GIG1 CCN1 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Cyr61 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | Cyr61 |
| Short name | Cyr61 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | 61 (Antibody to), ALEXA FLUOR 488, angiogenic inducer, cysteine-rich |
| Alternative technique | antibodies |
| Identity | 2654 |
| Gene | CYR61 |
| Long gene name | cysteine rich angiogenic inducer 61 |
| Synonyms gene | IGFBP10 |
| Synonyms gene name | 61 , angiogenic inducer, cysteine-rich |
| Locus | 1p22, 3 |
| Discovery year | 1998-03-02 |
| GenBank acession | AF031385 |
| Entrez gene record | 3491 |
| Pubmed identfication | 9135077 |
| RefSeq identity | NM_001554 |
| Classification | CYR61/CTGF/NOV matricellular proteins |
| Havana BLAST/BLAT | OTTHUMG00000010577 |