Name : Cyr61 Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN4776681376
| Long name | Biotin Conjugated, Cyr61 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Cyr61 |
| Specificity | This is a highly specific antibody against Cyr61 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen_range | 250-300/381 |
| Subcellular location | Secreted |
| Source | KLH conjugated synthetic peptide derived from human Cyr61 |
| Gene ID number | 3491 |
| Swiss Prot | O00622 |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Appears to play a role in wound healing by up-regulating, CYR61-mediated gene regulation is dependent on heparin-binding, Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1, MMP1, MMP3, PAI-1 and integrins alpha-3 and alpha-5, Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, TIMP1, VEGA-C, angiogenesis and cell adhesion, cell migration through integrin alpha-v/beta-5 and cell proliferation through integrin alpha-v/beta-3, chemotaxis, in skin fibroblasts, inflammation and matrix remodeling including VEGA-A, the expression of a number of genes involved in angiogenesis, uPA, Promotes cell proliferation |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Synonyms | CCN family member 1, CYR61, Cysteine-rich angiogenic inducer 61, GIG1, IBP-10, IGF-binding protein 10, IGFBP-10, IGFBP10, Insulin-like growth factor-binding protein 10, Protein CYR61, Protein GIG1, CCN1 |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Cyr61 Conjugated |
| Short name | Conjugated, Cyr61 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | 61 (Antibody to), angiogenic inducer, biotinilated coupled, cysteine-rich |
| Alternative technique | antibodies |