Name : Cyr61 Antibody, FITC Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN9002060188
| Long name | FITC Conjugated, Cyr61 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Cyr61 |
| Specificity | This is a highly specific antibody against Cyr61 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen_range | 250-300/381 |
| Subcellular location | Secreted |
| Source | KLH conjugated synthetic peptide derived from human Cyr61 |
| Gene ID number | 3491 |
| Swiss Prot | O00622 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Appears to play a role in wound healing by up-regulating, CYR61-mediated gene regulation is dependent on heparin-binding, Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1, MMP1, MMP3, PAI-1 and integrins alpha-3 and alpha-5, Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, TIMP1, VEGA-C, angiogenesis and cell adhesion, cell migration through integrin alpha-v/beta-5 and cell proliferation through integrin alpha-v/beta-3, chemotaxis, in skin fibroblasts, inflammation and matrix remodeling including VEGA-A, the expression of a number of genes involved in angiogenesis, uPA, Promotes cell proliferation |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Synonyms | CCN family member 1, CYR61, Cysteine-rich angiogenic inducer 61, GIG1, IBP-10, IGF-binding protein 10, IGFBP-10, IGFBP10, Insulin-like growth factor-binding protein 10, Protein CYR61, Protein GIG1, CCN1 |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Cyr61 Conjugated |
| Short name | FITC Conjugated, Cyr61 Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | FITC |
| Alternative name | 61 (Antibody to), angiogenic inducer, fluorecein coupled, cysteine-rich |
| Alternative technique | antibodies |