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Cystathionase Antibody

Cystathionase Antibody size: 0.1mg 389

Supplier NJS POLY
Price 389
Size 0.1mg
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenCystathionase
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ICC, IHC-P, WB
Recommended dilutions5-1ug/ml, 5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Immunocytochemistry: 0, Western blot: 0
Notes Titration of the Cystathionase antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented useThis Cystathionase antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P32929
PurityAntigen affinity
Description Cystathionine is physiologically activated by calcium and calmodulin, In some bacteria and mammals, Mutant mice lacking CTH displayed pronounced hypertension and diminished endothelium-dependent vasorelaxation, and other tissues, aorta, heart, including humans, this enzyme takes part in generating hydrogen sulfide and that genetic deletion of this enzyme in mice markedly reduced H2S levels in the serum, which is a mechanism for H2S formation in response to vascular activation, Cystathionine gamma lyase (from the CTH gene) is an enzyme which breaks down cystathionine into cysteine and alpha-ketobutyrate
ImmunogenAn amino acid sequence from the middle region of human Cystathionase (DVYGGTNRYFRQVASEFGLK) was used as the immunogen for this Cystathionase antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Cystathionase antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetCystathionase
Short nameCystathionase Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCystathionase (Antibody to)
Alternative techniqueantibodies
Identity 2501
Gene CTH
Long gene name cystathionine gamma-lyase
Synonyms gene name cystathionase (cystathionine gamma-lyase)
Locus 1p31, 1
Discovery year 1986-01-01
GenBank acession BC015807
Entrez gene record 1491
Pubmed identfication 1339280
RefSeq identity NM_001902
Havana BLAST/BLAT OTTHUMG00000009352

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