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Cystatin B Antibody / CSTB / Stefin B

Cystatin B Antibody / CSTB / Stefin B size: 0.1mg 406

Supplier NJS POLY
Price 406
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenCystatin B / CSTB / Stefin B
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, IHC-P, WB
Recommended dilutions1-0, 5-1ug/ml, 5ug/ml, IHC (Paraffin): 0, Western blot: 0
NotesOptimal dilution of the Cystatin B antibody should be determined by the researcher
Intented useThis Cystatin B antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P04080
PurityAntigen affinity
Description A cystatin B multiprotein complex might have a specific cerebellar function, CSTB becomes excluded from the nucleus and lysosomes, It has been isolated from human spleen and liver and its amino acid sequence has been fully determined, It is widely distributed and is localized mostly intracellularly, Its role is thought to be as a protector against the proteinases leaking from lysosomes, The cystatin B gene is located on 21q22, The protein is able to form a dimer stabilized by noncovalent forces, Upon differentiation to myotubes, also called STFB, and that the loss of this function might contribute to the etiopathogenesis of EPM1, but has been found extracellularly, h and b, inhibiting papain and cathepsins l, is a small protein that is a member of the superfamily of cysteine protease inhibitors, suggesting that the subcellular distribution of CSTB is dependent on the differentiation status of the cell, 3, Cystatin B (CSTB)
ImmunogenAmino acids 1-98 of human CSTB were used as the immunogen for the Cystatin B antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Cystatin B antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetCystatin B / CSTB / Stefin B
Short nameCystatin B Antibody / CSTB / Stefin B
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCystatin B (Antibody to) / cystatin B (stefin B) / Stefin B
Alternative techniqueantibodies
Alternative to gene target CST6 and EPM1 and EPM1A and PME and STFB and ULD, CSTB and IDBG-4888 and ENSG00000160213 and 1476, Cstb and IDBG-169100 and ENSMUSG00000005054 and 13014, nuclei, poly(A) RNA binding, this GO :0002020 and protease binding and molecular function this GO :0004866 and endopeptidase inhibitor activity and molecular function this GO :0004869 and cysteine-type endopeptidase inhibitor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005730 and nucleolus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0008344 and adult locomotory behavior and biological process this GO :0010466 and negative regulation of peptidase activity and biological process this GO :0010951 and negative regulation of endopeptidase activity and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0044822 and poly(A) RNA binding and molecular function this GO :0045861 and negative regulation of proteolysis and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0002020: protease binding, this GO :0002020: protease binding and also this GO :0004866: endopeptidase inhibitor activity and also this GO :0004869: cysteine-type endopeptidase inhibitor activity and also this GO :0005515: protein binding and also this GO :0044822: poly(A) RNA binding, this GO :0004866: endopeptidase inhibitor activity, this GO :0004869: cysteine-type endopeptidase inhibitor activity, this GO :0005515: protein binding, this GO :0044822: poly(A) RNA binding, cystatin B (stefin B)
Identity 2482
Gene CSTB
Long gene name cystatin B
Synonyms gene EPM1 STFB
Synonyms gene name cystatin B (stefin B)
Synonyms CST6 PME
Synonyms name stefin B
Locus 21q22, 3
Discovery year 1996-12-12
GenBank acession L03558
Entrez gene record 1476
Pubmed identfication 8596935
RefSeq identity NM_000100
Classification Cystatins, type 1
Havana BLAST/BLAT OTTHUMG00000086886
Locus Specific Databases LRG_485

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