Name : Cystatin C/CST3 Antibody, FITC Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN9983000828
| Long name | FITC Conjugated, Cystatin C/CST3 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Cystatin C/CST3 |
| Specificity | This is a highly specific antibody against Cystatin C/CST3 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from mouse Cystatin 3 |
| Gene ID number | 1471 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | A mutation in this gene has been associated with amyloid angiopathy, Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, Some of the members are active cysteine protease inhibitors, The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes, The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, There are three inhibitory families in the superfamily, This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases, [provided by RefSeq], establishing its role in vascular disease, including the type 1 cystatins(stefins), type 2 cystatins and the kininogens, where they appear to provide protective functions, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body, while others have lost or perhaps never acquired this inhibitory activity, The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Cystatin C/CST3 Conjugated |
| Short name | FITC Conjugated, Cystatin C/CST3 Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | FITC |
| Alternative name | fluorecein coupled, Cystatin C/CST3 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 2475 |
| Gene | CST3 |
| Long gene name | cystatin C |
| Synonyms gene name | cystatin C (amyloid angiopathy and cerebral hemorrhage) |
| Locus | 20p11, 21 |
| Discovery year | 1990-02-06 |
| Entrez gene record | 1471 |
| Pubmed identfication | 8486384 |
| RefSeq identity | NM_000099 |
| Classification | Cystatins, type 2 |
| Havana BLAST/BLAT | OTTHUMG00000032080 |