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Cystatin C/CST3 Antibody, FITC Conjugated

Cystatin C/CST3 Antibody, FITC Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name FITC Conjugated, Cystatin C/CST3 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCystatin C/CST3
SpecificityThis is a highly specific antibody against Cystatin C/CST3
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from mouse Cystatin 3
Gene ID number1471
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background A mutation in this gene has been associated with amyloid angiopathy, Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, Some of the members are active cysteine protease inhibitors, The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes, The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, There are three inhibitory families in the superfamily, This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases, [provided by RefSeq], establishing its role in vascular disease, including the type 1 cystatins(stefins), type 2 cystatins and the kininogens, where they appear to provide protective functions, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body, while others have lost or perhaps never acquired this inhibitory activity, The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetCystatin C/CST3 Conjugated
Short name FITC Conjugated, Cystatin C/CST3 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, Cystatin C/CST3 (Antibody to)
Alternative techniqueantibodies
Identity 2475
Gene CST3
Long gene name cystatin C
Synonyms gene name cystatin C (amyloid angiopathy and cerebral hemorrhage)
Locus 20p11, 21
Discovery year 1990-02-06
Entrez gene record 1471
Pubmed identfication 8486384
RefSeq identity NM_000099
Classification Cystatins, type 2
Havana BLAST/BLAT OTTHUMG00000032080

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