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Cytohesin 2 Antibody, ALEXA FLUOR 594

Cytohesin 2 Antibody, ALEXA FLUOR 594 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 594 Conjugated, Cytohesin 2 Polyclonal Antibody
Also known asAnti-Cytohesin 2 PAb ALEXA FLUOR 594
CategoryConjugated Primary Antibodies
Conjugated with 594, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCytohesin 2
SpecificityThis is a highly specific antibody against Cytohesin 2
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Cytohesin 2
Gene ID Number9266
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen A small group of GEFs which are insensitive to brefeldin-A (BFA) include cytohesin-1 (B2-1), All GEFs have a highly conserved Sec7 domain, All cytohesins function in the cell periphery and contain a pleckstrin homology (PH) domain, Arf has a number of disparate activities including maintenance of organelle integrity, Arf is found to be active when bound to GTP and inactive when bound to GDP, Arf is involved in intracellular protein traffic to and within the Golgi complex, Arfâ, GEF activity lies in the Sec7 domain and this activity has been shown to be inhibited by the fungal metabolite brefeldin-A (BFA), Like other small GTPases, Recruitment of the cytohesins to the membranes can occur in response to tyrosine kinase receptor activation, The PH domain has been shown to interact with phosphatidylinositol 3, This response appears to require the activation of phosphatidylinositol 3-kinase (PI 3-kinase), and cytohesin-4, as a co-factor for cholera toxin and as an activator of phospholipase D, assembly of coat proteins, cytohesin-2 (ARNO), cytohesin-3 (ARNO3), which are members of the Ras superfamily of regulatory GTP-binding proteins, &euro, &trade, 4, 5-triphosphate and is believed to promote membrane targeting of the cytohesins, The ADP-ribosylation factor (Arf) family comprises a group of structurally and functionally conserved 21 kDa proteins, s activation is dependent upon guanine nucleotide exchange factors (GEFs) which increase the rate of exchange of bound GDP with GTP
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission590nm/617nm
Synonyms CTS18, 1 Sec7p-L ARNO Sec7p-like cytohesin-2 CYTH2
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation 594, ALEXA FLUOR®, Alexa Fluor
ConjugatedAlexa conjugate 1
Gene targetCytohesin 2
Short nameCytohesin 2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 594
Alternative name ALEXA FLUOR 594, Cytohesin 2 (Antibody to)
Alternative techniqueantibodies
Identity 9503
Gene PSCD2L
Long gene name cytohesin 2
Synonyms gene PSCD2
Synonyms gene name Sec7 and coiled-coil domains 2 , Sec7 and coiled/coil domains 2 (cytohesin-2) pleckstrin homology, pleckstrin homology
Locus 19q13, 33
Discovery year 1998-11-19
GenBank acession X99753
Entrez gene record 9266
Pubmed identfication 8706128 8945478 20525696
RefSeq identity NM_004228
Classification Pleckstrin homology domain containing
Havana BLAST/BLAT OTTHUMG00000150245

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