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Dab1 (Tyr198) Antibody, ALEXA FLUOR 594

Dab1 (Tyr198) Antibody, ALEXA FLUOR 594 size: 100ul 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 350
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 594 Conjugated, Dab1 (Tyr198) Polyclonal Antibody
Also known asAnti-Dab1 Tyr198 PAb ALEXA FLUOR 594
CategoryConjugated Primary Antibodies
Conjugated with 594, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenDab1 Tyr198
SpecificityThis is a highly specific antibody against Dab1 Tyr198
ModificationPhosphorylation
Modification SiteTyr198
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human Dab1 around the phosphorylation site of Tyr198 [V(p-Y)QY]
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Dab1 has been shown to interact with the SH2 domains of Src, Dab2 (also designated DOC-2) is a mitogen-responsive phosphoprotein that binds the SH3 domain of Grb2, Evidence suggests that Dab1 functions downstream of Reelin in a signaling pathway involved in positioning cells in the developing brain (4), Fyn and Abl (1), Mutations in Dab1 result in widespread abnormalities in the brain, Reelin is a secreted protein thought to play a role in directing migrating neurons (3), This cytoplasmic protein is tyrosine-phosphorylated during rapid expansion of the developing nervous system, a homolog of the Drosophila Disabled protein, and it is thought to be a negative regulator of growth (5), and it is thought to interact with other proteins via a domain similar to the PTB domains of the Shc family, is an adaptor protein involved in neural development, similar to those seen in Reelin mutants (2), Dab1
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission590nm/617nm
Synonyms DAB1_HUMAN, Dab 1, Dab-1, Dab1, Dab1 Tyr198 , Disabled homolog 1, Disabled homolog 1 Drosophila, Scm, Scr, Scrambler, Yot, Yotari, Dab1 phospho Y198
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation 594, ALEXA FLUOR®, Alexa Fluor
ConjugatedAlexa conjugate 1
Gene targetDab1 (Tyr198)
Short nameDab1 (Tyr198) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 594
Alternative name ALEXA FLUOR 594, disabled homolog 1 (Drosophila) (Tyr198) (Antibody to)
Alternative techniqueantibodies

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