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Dab1 (Tyr198) Antibody, FITC Conjugated

Dab1 (Tyr198) Antibody, FITC Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, Dab1 (Tyr198) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenDab1 Tyr198
SpecificityThis is a highly specific antibody against Dab1 Tyr198
ModificationPhosphorylation
Modification siteTyr198
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human Dab1 around the phosphorylation site of Tyr198 [V(p-Y)QY]
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Dab1 has been shown to interact with the SH2 domains of Src, Dab2 (also designated DOC-2) is a mitogen-responsive phosphoprotein that binds the SH3 domain of Grb2, Evidence suggests that Dab1 functions downstream of Reelin in a signaling pathway involved in positioning cells in the developing brain (4), Fyn and Abl (1), Mutations in Dab1 result in widespread abnormalities in the brain, Reelin is a secreted protein thought to play a role in directing migrating neurons (3), This cytoplasmic protein is tyrosine-phosphorylated during rapid expansion of the developing nervous system, a homolog of the Drosophila Disabled protein, and it is thought to be a negative regulator of growth (5), and it is thought to interact with other proteins via a domain similar to the PTB domains of the Shc family, is an adaptor protein involved in neural development, similar to those seen in Reelin mutants (2), Dab1
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms DAB1_HUMAN, Dab 1, Dab-1, Dab1, Dab1 Tyr198 , Disabled homolog 1, Disabled homolog 1 Drosophila, Scm, Scr, Scrambler, Yot, Yotari, Dab1 phospho Y198
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetDab1 (Tyr198) Conjugated
Short name FITC Conjugated, Dab1 (Tyr198) Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, disabled homolog 1 (Drosophila) (Tyr198) (Antibody to)
Alternative techniqueantibodies

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