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DARPP-32 Antibody

DARPP-32 Antibody size: 0.1mg 406

Supplier NJS POLY
Price 406
Size 0.1mg
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenDARPP-32
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications IHC-P, WB
Recommended dilutions1-0, 5-1ug/ml, 5ug/ml, IHC (Paraffin): 0, Western blot: 0
NotesOptimal dilution of the DARPP-32 antibody should be determined by the researcher
Intented useThis DARPP-32 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q9UD71
PurityAntigen affinity
Description As a target for dopamine, Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor, Multiple transcript variants encoding different isoforms have been found for this gene, This gene encodes a bifunctional signal transduction molecule, also known as dopamine- and cAMP-regulated neuronal phosphoprotein (DARPP-32), is a protein that in humans is encoded by the PPP1R1B gene, this gene may serve as a therapeutic target for neurologic and psychiatric disorders, Protein phosphatase 1 regulatory subunit 1B (PPP1R1B)
ImmunogenAmino acids MDPKDRKKIQFSVPAPPSQLDPRQVEMIRRRRPTPA of human DARPP-32 were used as the immunogen for the DARPP-32 antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the DARPP-32 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term
Localization minor nuclear, Cytoplasmic
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetDARPP-32
Short nameDARPP-32 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameDARPP-32 (Antibody to)
Alternative techniqueantibodies
Identity 9287
Gene PPP1R1B
Long gene name protein phosphatase 1 regulatory inhibitor subunit 1B
Synonyms gene name protein phosphatase 1, regulatory (inhibitor) subunit 1B
Synonyms DARPP-32 FLJ20940
Synonyms name dopamine and cAMP regulated phosphoprotein
Locus 17q12
Discovery year 1993-01-22
GenBank acession AI124650
Entrez gene record 84152
Pubmed identfication 8120638
RefSeq identity NM_032192
Classification Protein phosphatase 1 regulatory subunits
Havana BLAST/BLAT OTTHUMG00000133210

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