Name : DC-SIGN Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN5396710398
| Long name | ALEXA FLUOR 488 Conjugated, DC-SIGN Polyclonal Antibody |
| Also known as | Anti-DC-SIGN PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | DC-SIGN |
| Specificity | This is a highly specific antibody against DC-SIGN |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DC-SIGN/CD209 |
| Gene ID Number | 30835 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | A DC-SIGN homologue (termed CD299, DC-SIGN forms a novel gene family with DC-SIGNR and many alternatively spliced isoforms of DC-SIGN and DC-SIGNR, DC-SIGNR, DCs also amplify the amount of virus and extend the duration of viral infectivity, HIV2 and SIV bind to DCs via DCSIGN, ICAM3 is the natural ligand for DC-SIGN, L-SIGN and DCSIGN2) was identified recently, Multiple strains of HIV1, The expression of DC-SIGN was found in mucosal tissues including placenta, and rectum, small intestine, where DCs hand over HIV to CD4+ T lymphocytes, Dendritic cells (DCs) that control immune responses were recently found to capture and transport HIV from the mucosal area to remote lymph nodes |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | DC-SIGN CDSIGN DC-SIGN1 CLEC4L |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the DC-SIGN Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | DC-SIGN |
| Short name | DC-SIGN Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, DC-SIGN (Antibody to) |
| Alternative technique | antibodies |
| Identity | 1641 |
| Gene | CD209 |
| Long gene name | CD209 molecule |
| Synonyms gene name | CD209 antigen |
| Locus | 19p13, 2 |
| Discovery year | 2000-07-19 |
| GenBank acession | M98457 |
| Entrez gene record | 30835 |
| Pubmed identfication | 1518869 |
| RefSeq identity | NM_021155 |
| Classification | CD molecules Scavenger receptors C-type lectin domain family |
| Havana BLAST/BLAT | OTTHUMG00000182530 |