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DC-SIGN Antibody, FITC Conjugated

DC-SIGN Antibody, FITC Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name FITC Conjugated, DC-SIGN Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenDC-SIGN
SpecificityThis is a highly specific antibody against DC-SIGN
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from human DC-SIGN/CD209
Gene ID number30835
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
CrossreactivityHuman
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background A DC-SIGN homologue (termed CD299, DC-SIGN forms a novel gene family with DC-SIGNR and many alternatively spliced isoforms of DC-SIGN and DC-SIGNR, DC-SIGNR, DCs also amplify the amount of virus and extend the duration of viral infectivity, HIV2 and SIV bind to DCs via DCSIGN, ICAM3 is the natural ligand for DC-SIGN, L-SIGN and DCSIGN2) was identified recently, Multiple strains of HIV1, The expression of DC-SIGN was found in mucosal tissues including placenta, and rectum, small intestine, where DCs hand over HIV to CD4+ T lymphocytes, Dendritic cells (DCs) that control immune responses were recently found to capture and transport HIV from the mucosal area to remote lymph nodes
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms DC-SIGN CDSIGN DC-SIGN1 CLEC4L
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetDC-SIGN Conjugated
Short name FITC Conjugated, DC-SIGN Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, DC-SIGN (Antibody to)
Alternative techniqueantibodies
Identity 1641
Gene CD209
Long gene name CD209 molecule
Synonyms gene name CD209 antigen
Locus 19p13, 2
Discovery year 2000-07-19
GenBank acession M98457
Entrez gene record 30835
Pubmed identfication 1518869
RefSeq identity NM_021155
Classification CD molecules Scavenger receptors C-type lectin domain family
Havana BLAST/BLAT OTTHUMG00000182530

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