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DCAMKL1 Antibody

DCAMKL1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameDCAMKL1 Primary Polyclonal Antibody
Also known asDCAMKL1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenDCAMKL1
SpecificityThis is a highly specific antibody against DCAMKL1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DCAMKL1
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen All three proteins are highly expressed in developing brain and may function together to regulate microtubules involved in neuronal migration, Genetic analysis has identified two proteins that are mutated in some cases of lissencephaly, In addition, LIS1 displays sequence homology to ?subunits of heterotrimeric G proteins, The DCAMKL1 protein encodes a functional kinase that is capable of phosphorylating myelin basic protein and itself, and doublecortin contains a consensus Abl phosphorylation site, but its kinase activity does not appear to affect its microtubule polymerization activity, designated lissencephaly-1 protein (LIS1) and doublecortin, manifesting as severe mental retardation, the DCAMKL1 (doublecortin-like and CAM kinase-like 1) protein shows homology to doublecortin, Lissencephaly (smooth brain) is an abnormality of brain development characterized by incomplete neuronal migration and a smooth cerebral surface
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Cpg16, DCLK1_HUMAN, Dcl, Dclk, Dclk1, Doublecortin domain-containing protein 3A, Doublecortin-like and CAM kinase-like 1, Doublecortin-like kinase 1, KIAA0369, Serine/threonine-protein kinase DCAMKL1, Serine/threonine-protein kinase DCLK1, Calcium/calmodulin-dependent protein kinase type I-like CPG16
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetDCAMKL1
Short nameDCAMKL1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameDCAMKL1 (Antibody to)
Alternative techniqueantibodies
Identity 2700
Gene DCLK1
Long gene name doublecortin like kinase 1
Synonyms gene DCAMKL1
Synonyms gene name doublecortin and CaM kinase-like 1 doublecortin-like kinase 1
Synonyms KIAA0369 DCLK DCDC3A
Locus 13q13, 3
Discovery year 1999-02-22
GenBank acession AB002367
Entrez gene record 9201
Pubmed identfication 9747029 10036192
RefSeq identity NM_004734
Classification Doublecortin superfamily
Havana BLAST/BLAT OTTHUMG00000016729

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