Filters

DCAMKL1 Antibody, FITC Conjugated

DCAMKL1 Antibody, FITC Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name FITC Conjugated, DCAMKL1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenDCAMKL1
SpecificityThis is a highly specific antibody against DCAMKL1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human DCAMKL1
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background All three proteins are highly expressed in developing brain and may function together to regulate microtubules involved in neuronal migration, Genetic analysis has identified two proteins that are mutated in some cases of lissencephaly, In addition, LIS1 displays sequence homology to ?subunits of heterotrimeric G proteins, The DCAMKL1 protein encodes a functional kinase that is capable of phosphorylating myelin basic protein and itself, and doublecortin contains a consensus Abl phosphorylation site, but its kinase activity does not appear to affect its microtubule polymerization activity, designated lissencephaly-1 protein (LIS1) and doublecortin, manifesting as severe mental retardation, the DCAMKL1 (doublecortin-like and CAM kinase-like 1) protein shows homology to doublecortin, Lissencephaly (smooth brain) is an abnormality of brain development characterized by incomplete neuronal migration and a smooth cerebral surface
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms KIAA0369 DCLK DCDC3A
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetDCAMKL1 Conjugated
Short name FITC Conjugated, DCAMKL1 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, DCAMKL1 (Antibody to)
Alternative techniqueantibodies
Identity 2700
Gene DCLK1
Long gene name doublecortin like kinase 1
Synonyms gene DCAMKL1
Synonyms gene name doublecortin and CaM kinase-like 1 doublecortin-like kinase 1
Locus 13q13, 3
Discovery year 1999-02-22
GenBank acession AB002367
Entrez gene record 9201
Pubmed identfication 9747029 10036192
RefSeq identity NM_004734
Classification Doublecortin superfamily
Havana BLAST/BLAT OTTHUMG00000016729

Subscribe to our Newsletter