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DCX Antibody

DCX Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenDCX
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, WB, IHC
Recommended dilutionsIHC (Paraffin): 1:10-1:50, Western blot: 1:1000
NotesTitration of the DCX antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis DCX antibodyis to be used only for research purposes and not for diagnostics
Uniprot #O43602
PurityAntigen affinity
Description DCX is a cytoplasmic protein which appears to direct neuronal migration by regulating the organization and stability of microtubules, In addition, It contains two doublecortin domains, Mutations in the gene encoding DCX are a cause of X-linked lissencephaly, and this interaction is important to proper microtubule function in the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation, the regulatory gamma subunit of platelet activating factor acetylhydrolase, this protein interacts with LIS1, which bind microtubules, In the developing cortex
ImmunogenA portion of amino acids 107-137 from the human protein was used as the immunogen for this DCX antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the DCX antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetDCX
Short nameDCX Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameDCX (Antibody to)
Alternative techniqueantibodies
Identity 2714
Gene DCX
Long gene name doublecortin
Synonyms gene name X-linked (doublecortin) , doublecortex, lissencephaly
Synonyms SCLH DC LISX DBCN XLIS
Synonyms name doublecortex
Locus Xq23
Discovery year 1998-03-24
GenBank acession AF040254
Entrez gene record 1641
Pubmed identfication 9489699 9489700
RefSeq identity NM_178153
Classification Doublecortin superfamily
Havana BLAST/BLAT OTTHUMG00000022204

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