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DD1/AKR1C1/DD2 Antibody

DD1/AKR1C1/DD2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameDD1/AKR1C1/DD2 Primary Polyclonal Antibody
Also known asDD1/AKR1C1/DD2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenDD1/AKR1C1/DD2
SpecificityThis is a highly specific antibody against DD1/AKR1C1/DD2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DD1
Gene ID number1645
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivityHuman
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen AKR1C3 and 3alpha-HSD are alternate designations for human DD3 (which is referred to as AKR1C18 in rodents), BABP or DDH2, CD, CHDR or AKR1C6 (in rodents), DD1 and DD2 are 20alpha-HSDs, DD1 and DD2 are ubiquitously expressed, DD3 is a unique enzyme that can specifically catalyze the dehydrogenation of trans-benzenedihydrodiol and trans-naphthalenedihydrodiol, DDH or DDH1, NADPH-dependent oxidoreductase that reduces 3-keto-5-dihydrosteroids to their tetrahydro products, The 20alpha-HSD catalyzes the reaction of progesterone to the inactive form 20alpha-hydroxyprogesterone, The 3alpha-HSD is a cytosolic, The multiple human cytosolic dihydrodiol dehydrogenases are involved in the metabolism of xenobiotics, and are responsible for the reduction of ketone-containing drugs by using NADH or NADPH as a cofactor, dDD, monomeric, pesticides and steroid hormones, such as polycyclic aromatic hydrocarbons, whereas DD3 and DD4 are the 3alpha-HSDs, whereas DD4 mRNA is restricted to the liver, while DD2 also can be designated AKR1C2, while DD4 also can be called AKR1C4, DD1 is also designated AKR1C1
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names 2-diol dehydrogenase, 20 ALPHA HSD, 20 alpha 3 alpha hydroxysteroid dehydrogenase, 20 alpha hydroxysteroid dehydrogenase, 20-alpha-HSD, 20-alpha-hydroxysteroid dehydrogenase, 20ALPHAHSD, 2ALPHAHSD, AK1C1, AK1C1_HUMAN, AKR1C1, Aldo keto reductase family 1 member C1, Aldo-keto reductase family 1 member C1, C9, Chlordecone reductase homolog, Chlordecone reductase homolog HAKRC, DD1, DD1/DD2, DDH, DDH1, Dihydrodiol dehydrogenase 1, Dihydrodiol dehydrogenase 1/2, H37, HAKRC, HBAB, Hepatic dihydrodiol dehydrogenase, High affinity hepatic bile acid-binding protein, High-affinity hepatic bile acid-binding protein, Indanol dehydrogenase, MBAB, MGC8954, Trans-1, Trans-1, Type II 3 alpha hydroxysteroid dehydrogenase, dihydrodiol dehydrogenase isoform DD1, 2 dihydrobenzene 1, 2 diol dehydrogenase, 2-dihydrobenzene-1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetDD1/AKR1C1/DD2
Short nameDD1/AKR1C1/DD2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameDD1/AKR1C1/DD2 (Antibody to)
Alternative techniqueantibodies
Identity 385
Gene AKR1C2
Long gene name aldo-keto reductase family 1 member C2
Synonyms gene DDH2 TDD
Synonyms gene name 3-alpha hydroxysteroid dehydrogenase, aldo-keto reductase family 1, bile acid binding protein, member C2 (dihydrodiol dehydrogenase 2, type III) testicular 17, 20-desmolase deficiency
Synonyms DD BABP DD2 HAKRD MCDR2
Synonyms name 3-alpha hydroxysteroid dehydrogenase, bile acid binding protein, dihydrodiol dehydrogenase 2, type III
Locus 10p15, 1
Discovery year 1994-09-14
GenBank acession L32592
Entrez gene record 1646
Pubmed identfication 9716498 21802064
RefSeq identity NM_001354
Classification Aldo-keto reductases
Havana BLAST/BLAT OTTHUMG00000017584

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