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DDR1 (1464CT339.1.54) Monoclonal Antibody

DDR1 (1464CT339.1.54) Monoclonal Antibody size: 0.1ml 211

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 211
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name1, 54) Monoclonal Antibody, DDR1 (1464CT339
Also known as1, 54) Monoclonal Antibody, DDR1 (1464CT339
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenDDR1
SpecificityThis is a highly specific antibody against DDR1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityMonoclonal
Clone number1, 1464CT339, 54
SourceThis DDR1 antibody is generated from a mouse immunized with a recombinant protein
Gene ID number780
Swiss ProtQ08345
Tested Applications IHC-P, WB
Recommended dilutions WB(1:1000), IHC-P(1:25)
Cross reactivityHuman
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Also plays a role in tumor cell invasion, Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases, MMP7 and MMP9, Phosphorylates PTPN11, Promotes smooth muscle cell migration, Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, Required for normal blastocyst implantation during pregnancy, Required for normal ear morphology and normal hearing (By similarity), and thereby contributes to arterial wound healing, and thereby facilitates cell migration and wound healing, cell migration, differentiation, for normal mammary gland differentiation and normal lactation, remodeling of the extracellular matrix, survival and cell proliferation, Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CD167, CD167 antigen-like family member A, CD167a, Cell adhesion kinase, DDR, DDR1, Discoidin receptor tyrosine kinase, EDDR1, Epithelial discoidin domain receptor 1, Epithelial discoidin domain-containing receptor 1, HGK2, MCK-10, MCK10, Mammary carcinoma kinase 10, NEP, NTRK4, PTK3, PTK3A, Protein-tyrosine kinase 3A, Protein-tyrosine kinase RTK-6, RTK6, TRK E, TRKE, Tyrosine kinase DDR, Tyrosine-protein kinase CAK, CAK
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene target1, 54) Monoclonal, DDR1 (1464CT339
Short name1, 54) Monoclonal Antibody, DDR1 (1464CT339
Technique Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative name1, 54) monoclonal (Antibody to), discoidin domain receptor tyrosine kinase 1 (1464CT339
Alternative techniqueantibodies
Alternative to gene target CAK and CD167 and DDR and EDDR1 and HGK2 and MCK10 and NEP and NTRK4 and PTK3 and PTK3A and RTK6 and TRKE, DDR1 and IDBG-634478 and ENSBTAG00000010682 and 534092, DDR1 and IDBG-76157 and ENSG00000204580 and 100616237, Ddr1 and IDBG-178873 and ENSMUSG00000003534 and 12305, Extracellular, spreading of cells and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0046872 and metal ion binding and molecular function this GO :0060444 and branching involved in mammary gland duct morphogenesis and biological process this GO :0060749 and mammary gland alveolus development and biological process this GO :0061302 and smooth muscle cell-matrix adhesion and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0001558 and regulation of cell growth and biological process this GO :0001952 and regulation of cell-matrix adhesion and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004714 and transmembrane receptor protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005518 and collagen binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007155 and cell adhesion and biological process this GO :0007566 and embryo implantation and biological process this GO :0007595 and lactation and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0010715 and regulation of extracellular matrix disassembly and biological process this GO :0014909 and smooth muscle cell migration and biological process this GO :0016772 and transferase activity, this GO :0004672: protein kinase activity, this GO :0004672: protein kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0004714: transmembrane receptor protein tyrosine kinase activity and also this GO :0005515: protein binding and also this GO :0005518: collagen binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0004714: transmembrane receptor protein tyrosine kinase activity, this GO :0005515: protein binding, this GO :0005518: collagen binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, this GO :0038062: protein tyrosine kinase collagen receptor activity, this GO :0046872: metal ion binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0038062: protein tyrosine kinase collagen receptor activity and also this GO :0046872: metal ion binding, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0038062 and protein tyrosine kinase collagen receptor activity and molecular function this GO :0038063 and collagen-activated tyrosine kinase receptor signaling pathway and biological process this GO :0038083 and peptidyl-tyrosine autophosphorylation and biological process this GO :0043235 and receptor complex and cellular component this GO :0043583 and ear development and biological process this GO :0044319 and wound healing, 780, discoidin domain receptor tyrosine kinase 1
Identity 2730
Gene DDR1
Long gene name discoidin domain receptor tyrosine kinase 1
Synonyms gene NTRK4 PTK3A NEP CAK EDDR1
Synonyms gene name discoidin domain receptor family, member 1
Synonyms RTK6 CD167
Locus 6p21, 33
Discovery year 1994-08-29
GenBank acession X99031
Entrez gene record 780
Pubmed identfication 7789998
RefSeq identity NM_013994
Classification CD molecules Receptor Tyrosine Kinases
Havana BLAST/BLAT OTTHUMG00000031236

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