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DDR1 Antibody

DDR1 Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormPurified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenDDR1
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, FACS, IF, IHC, WB
Recommended dilutionsFlow Cytometry: 1:10-1:50, IHC (Paraffin): 1:10-1:50, Immunofluorescence: 1:10-1:50, Western blot: 1:1000
NotesTitration of the DDR1 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis DDR1 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q08345
PurityPurified
Description DDR1 is an RTK that is widely expressed in normal and transformed epithelial cells and is activated by various types of collagen, In addition, In situ studies and Northern-blot analysis show that expression of DDR1 is restricted to epithelial cells, It belongs to a subfamily of tyrosine kinase receptors with a homology region to the Dictyostelium discoideum protein discoidin I in their extracellular domain, Its autophosphorylation is achieved by all collagens so far tested (type I to type VI), These molecules are involved in the regulation of cell growth, and brain, and pediatric brain, differentiation and metabolism, esophageal, gastrointestinal tract, it is significantly over-expressed in several human tumors from breast, lung, ovarian, particularly in the kidney, Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment
ImmunogenA portion of amino acids 299-330 from the human protein was used as the immunogen for this DDR1 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the DDR1 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetDDR1
Short nameDDR1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namediscoidin domain receptor tyrosine kinase 1 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target CAK and CD167 and DDR and EDDR1 and HGK2 and MCK10 and NEP and NTRK4 and PTK3 and PTK3A and RTK6 and TRKE, DDR1 and IDBG-634478 and ENSBTAG00000010682 and 534092, DDR1 and IDBG-76157 and ENSG00000204580 and 100616237, Ddr1 and IDBG-178873 and ENSMUSG00000003534 and 12305, Extracellular, spreading of cells and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0046872 and metal ion binding and molecular function this GO :0060444 and branching involved in mammary gland duct morphogenesis and biological process this GO :0060749 and mammary gland alveolus development and biological process this GO :0061302 and smooth muscle cell-matrix adhesion and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0001558 and regulation of cell growth and biological process this GO :0001952 and regulation of cell-matrix adhesion and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004714 and transmembrane receptor protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005518 and collagen binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007155 and cell adhesion and biological process this GO :0007566 and embryo implantation and biological process this GO :0007595 and lactation and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0010715 and regulation of extracellular matrix disassembly and biological process this GO :0014909 and smooth muscle cell migration and biological process this GO :0016772 and transferase activity, this GO :0004672: protein kinase activity, this GO :0004672: protein kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0004714: transmembrane receptor protein tyrosine kinase activity and also this GO :0005515: protein binding and also this GO :0005518: collagen binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0004714: transmembrane receptor protein tyrosine kinase activity, this GO :0005515: protein binding, this GO :0005518: collagen binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, this GO :0038062: protein tyrosine kinase collagen receptor activity, this GO :0046872: metal ion binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0038062: protein tyrosine kinase collagen receptor activity and also this GO :0046872: metal ion binding, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0038062 and protein tyrosine kinase collagen receptor activity and molecular function this GO :0038063 and collagen-activated tyrosine kinase receptor signaling pathway and biological process this GO :0038083 and peptidyl-tyrosine autophosphorylation and biological process this GO :0043235 and receptor complex and cellular component this GO :0043583 and ear development and biological process this GO :0044319 and wound healing, 780, discoidin domain receptor tyrosine kinase 1
Identity 2730
Gene DDR1
Long gene name discoidin domain receptor tyrosine kinase 1
Synonyms gene NTRK4 PTK3A NEP CAK EDDR1
Synonyms gene name discoidin domain receptor family, member 1
Synonyms RTK6 CD167
Locus 6p21, 33
Discovery year 1994-08-29
GenBank acession X99031
Entrez gene record 780
Pubmed identfication 7789998
RefSeq identity NM_013994
Classification CD molecules Receptor Tyrosine Kinases
Havana BLAST/BLAT OTTHUMG00000031236

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