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DDX5 (Tyr593) Antibody, ALEXA FLUOR 350

DDX5 (Tyr593) Antibody, ALEXA FLUOR 350 size: 100ul 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 350
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 350 Conjugated, DDX5 (Tyr593) Polyclonal Antibody
Also known asAnti-DDX5 Tyr593 PAb ALEXA FLUOR 350
CategoryConjugated Primary Antibodies
Conjugated with 350, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenDDX5 Tyr593
SpecificityThis is a highly specific antibody against DDX5 Tyr593
ModificationPhosphorylation
Modification SiteTyr593
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range577-605/614
Subcellular locationNucleus
SourceKLH conjugated synthetic phosphopeptide derived from human DDX5 around the phosphorylation site of Tyr593
Gene ID Number1655
Swiss ProtP17844
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Acts as transcriptional repressor in a promoter-specicic manner, As component of a large PER complex is involved in the inhibition of 3' transcriptional termination of circadian target genes such as PER1 and NR1D1 and the control of the circadian rhythms, Binds to the tau pre-mRNA in the stem-loop region downstream of exon 10, Increases ESR1 AF-1 domain-mediated transactivation and ESR1 AF-1 and AF-2 domains transcriptional synergistic activity, Involved in transcriptional regulation, Synergizes with DDX17 and SRA1 RNA to activate MYOD1 transcriptional activity and involved in skeletal muscle differentiation, The rate of ATP hydrolysis is highly stimulated by single-stranded RNA, Transcriptional coactivator for RUNX2 and involved in regulation of osteoblast differentiation, Transcriptional coactivator for estrogen receptor ESR1 and androgen receptor AR, Transcriptional coactivator for p53/TP53 and involved in p53/TP53 transcriptional response to DNA damage and p53/TP53-dependent apoptosis, its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner, such as HDAC1, the function is independent of the RNA helicase activity, the function probbaly involves association with histone deacetylases, Involved in the alternative regulation of pre-mRNA splicing
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission343nm/442nm
Synonyms p68
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 350, Alexa Fluor
Gene targetDDX5 (Tyr593)
Short nameDDX5 (Tyr593) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 350
Alternative name ALEXA FLUOR 350, DDX5 (Tyr593) (Antibody to)
Alternative techniqueantibodies
Identity 2746
Gene DDX5
Long gene name DEAD-box helicase 5
Synonyms gene HLR1 G17P1
Synonyms gene name 68kD) DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 , DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 5 (RNA helicase
Locus 17q23, 3
Discovery year 1989-06-30
GenBank acession AF015812
Entrez gene record 1655
Pubmed identfication 22156369 18698352
RefSeq identity NM_004396
Classification DEAD-box helicases
Havana BLAST/BLAT OTTHUMG00000178936

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