Name : Deltex 1 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN6583382092
| Long name | Deltex 1 Primary Polyclonal Antibody |
| Also known as | Deltex 1 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | Deltex 1 |
| Specificity | This is a highly specific antibody against Deltex 1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 370-420/620 |
| Subcellular location | Nucleus, Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Deltex-1 |
| Gene ID number | 1840 |
| Swiss Prot | Q86Y01 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Involved in neurogenesis, Mainly acts as a positive regulator of Notch, Mediates the antineural activity of Notch, Promotes B-cell development at the expense of T-cell development, Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations, and may also be involved in MZB (Marginal zone B) cell differentiation, but it also acts as a negative regulator, depending on the developmental and cell context, lymphogenesis and myogenesis, mediating ubiquitination and promoting degradation of MEKK1, possibly by inhibiting the transcriptional activation mediated by MATCH1, suggesting that it can antagonize NOTCH1, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity (By similarity), Functions as a ubiquitin ligase protein in vivo |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | DTX1, Deltex1, E3 ubiquitin-protein ligase DTX1, Protein deltex-1, hDTX1, hDx-1 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Deltex 1 |
| Short name | Deltex 1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Deltex 1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 3060 |
| Gene | DTX1 |
| Long gene name | deltex E3 ubiquitin ligase 1 |
| Synonyms gene name | deltex homolog 1 (Drosophila) |
| Synonyms | hDx-1 |
| Locus | 12q24, 13 |
| Discovery year | 1998-05-15 |
| GenBank acession | AF053700 |
| Entrez gene record | 1840 |
| Pubmed identfication | 9590294 12670957 |
| Havana BLAST/BLAT | OTTHUMG00000169610 |