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Dematin Antibody, Cy7 Conjugated

Dematin Antibody, Cy7 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy7 Conjugated, Dematin Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationCy7
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenDematin
SpecificityThis is a highly specific antibody against Dematin
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range250-280/405
Subcellular locationCytoplasm
SourceKLH conjugated synthetic peptide derived from human Dematin
Gene ID number2039
Swiss ProtQ08495
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Acts as a tumor suppressor and inhibits malignant cell transformation, Also required for the formation of a diverse set of cell protrusions, Binds to the erythrocyte membrane glucose transporter-1 SLC2A1/GLUT1, In platelets, Its F-actin-bundling activity is reversibly regulated upon its phosphorylation by the cAMP-dependent protein kinase A (PKA), Plays a role in maintaining the functional integrity of PKA-activated erythrocyte shape and the membrane mechanical properties, Plays also a role as a modulator of actin dynamics in fibroblasts, acts as a negative regulator of the RhoA activation pathway, and hence stabilizes and attaches the spectrin-actin network to the erythrocytic plasma membrane, functions as a regulator of internal calcium mobilization across the dense tubular system that affects platelet granule secretion pathways and aggregation, motility and migration, necessary for platelet cell spreading, such as filopodia and lamellipodia, Membrane-cytoskeleton-associated protein with F-actin-binding activity that induces F-actin bundles formation and stabilization
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission743nm/767nm
Synonyms DMTN, Dematin, Dematin actin-binding protein, EPB49, Erythrocyte membrane protein band 4, 9, DMT
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths
Gene targetDematin Conjugated
Short name Conjugated, Dematin Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy7
Alternative name cyanine 7 coupled, Dematin (Antibody to)
Alternative techniqueantibodies

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