Name : DEPTOR Antibody, ALEXA FLUOR 647
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN9532952790
| Long name | ALEXA FLUOR 647 Conjugated, DEPTOR Polyclonal Antibody |
| Also known as | Anti-DEPTOR PAb ALEXA FLUOR 647 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 647, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | DEPTOR |
| Specificity | This is a highly specific antibody against DEPTOR |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 62-107/409 |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DEPTOR/DEPDC6 |
| Gene ID Number | 64798 |
| Swiss Prot | Q8TB45 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Chromosome 8 consists of nearly 146 million base pairs, Containing two DEP domains and one PDZ (DHR) domain, DEPTOR interacts with FRAP via its PDZ domain, DEPTOR is encoded by a gene that maps to human chromosome 8q24, Pfeiffer syndrome, Schizophrenia, Trisomy 8, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8, also known as DEP, and undergoes post-translational phosphorylation, bipolar disorder, congenital hypothyroidism, encodes over 800 genes and is associated with a variety of diseases and malignancies, is a 409 amino acid protein that negatively regulates mTORC1 and mTORC2 pathways, 12, 6 or DEPDC6 (DEP domain-containing protein 6), DEPTOR (DEP domain containing MTOR-interacting protein) |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 650nm/665nm |
| Synonyms | DEP, 6 FLJ12428 |
| Properties | ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the DEPTOR Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 647, Alexa Fluor |
| Gene target | DEPTOR |
| Short name | DEPTOR Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 647 |
| Alternative name | ALEXA FLUOR 647, DEP domain containing Mammalian target on rapamycin-interacting protein (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | BT, DEPTOR and IDBG-34051 and ENSG00000155792 and 64798, Deptor and IDBG-141160 and ENSMUSG00000022419 and 97998, multiple, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0006469 and negative regulation of protein kinase activity and biological process this GO :0032007 and negative regulation of TOR signaling and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0045792 and negative regulation of cell size and biological process this GO :2001236 and regulation of extrinsic apoptotic signaling pathway and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding, 28648 and IDBG-645663 and ENSBTAG00000015341 and 617606, DEP domain containing MTOR-interacting protein |
| Identity | 22953 |
| Gene | DEPTOR |
| Long gene name | DEP domain containing MTOR interacting protein |
| Synonyms gene | DEPDC6 |
| Synonyms gene name | DEP domain containing 6 |
| Locus | 8q24, 12 |
| Discovery year | 2004-02-23 |
| Entrez gene record | 64798 |
| Pubmed identfication | 19446321 |
| RefSeq identity | NM_022783 |
| Classification | PDZ domain containing |
| Havana BLAST/BLAT | OTTHUMG00000165052 |