Name : DERLIN-1 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN2967294692
| Long name | DERLIN-1 Primary Polyclonal Antibody |
| Also known as | DERLIN-1 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | DERLIN-1 |
| Specificity | This is a highly specific antibody against DERLIN-1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DERLIN-1 |
| Gene ID number | 79139 |
| Tested Applications | IF(IHC-P), IHC-P |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Derlin proteins are multi-pass membrane proteins localizing to the ER, Derlin-1, Derlins are involved in transferring misfolded proteins from the ER to the cytosol, Derlins may also be important for cell proliferation, In the case of cytomegalovirus infection, also designated Derlins or DERtrins, are crucial for the degradation of misfolded endoplasmic reticulum (ER) luminal proteins, as opposed to Derlins-2 and -3, is involved in the export of MHC class I heavy chains from the ER via its interaction with the viral protein US11, where the misfolded proteins are destroyed in an ubiquitin-dependent manner by the proteasome, Degradation in endoplasmic reticulum proteins |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | DER 1, DER-1, DER1, DERL1_HUMAN, Derlin 1, Derlin1, Derlin1 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | DERLIN-1 |
| Short name | DERLIN-1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | DERLIN-1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 28454 |
| Gene | DERL1 |
| Long gene name | derlin 1 |
| Synonyms gene name | Der1-like domain family, member 1 |
| Synonyms | MGC3067 PRO2577 FLJ13784 DER1 DER-1 derlin-1 |
| Locus | 8q24, 13 |
| Discovery year | 2004-11-02 |
| GenBank acession | BC002457 |
| Entrez gene record | 79139 |
| Pubmed identfication | 12975309 15215855 |
| RefSeq identity | NM_024295 |
| Classification | Rhomboid family |
| Havana BLAST/BLAT | OTTHUMG00000165080 |