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DERLIN-1 Antibody

DERLIN-1 Antibody size: 0.1ml 263

Price 263
Size 0.1ml
Long nameDERLIN-1 Primary Polyclonal Antibody
Also known asDERLIN-1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenDERLIN-1
SpecificityThis is a highly specific antibody against DERLIN-1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DERLIN-1
Gene ID number79139
Tested Applications IF(IHC-P), IHC-P
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Derlin proteins are multi-pass membrane proteins localizing to the ER, Derlin-1, Derlins are involved in transferring misfolded proteins from the ER to the cytosol, Derlins may also be important for cell proliferation, In the case of cytomegalovirus infection, also designated Derlins or DERtrins, are crucial for the degradation of misfolded endoplasmic reticulum (ER) luminal proteins, as opposed to Derlins-2 and -3, is involved in the export of MHC class I heavy chains from the ER via its interaction with the viral protein US11, where the misfolded proteins are destroyed in an ubiquitin-dependent manner by the proteasome, Degradation in endoplasmic reticulum proteins
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names DER 1, DER-1, DER1, DERL1_HUMAN, Derlin 1, Derlin1, Derlin1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetDERLIN-1
Short nameDERLIN-1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameDERLIN-1 (Antibody to)
Alternative techniqueantibodies
Identity 28454
Gene DERL1
Long gene name derlin 1
Synonyms gene name Der1-like domain family, member 1
Synonyms MGC3067 PRO2577 FLJ13784 DER1 DER-1 derlin-1
Locus 8q24, 13
Discovery year 2004-11-02
GenBank acession BC002457
Entrez gene record 79139
Pubmed identfication 12975309 15215855
RefSeq identity NM_024295
Classification Rhomboid family
Havana BLAST/BLAT OTTHUMG00000165080

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