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DERP6 Antibody

DERP6 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameDERP6 Primary Polyclonal Antibody
Also known asDERP6 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenDERP6
SpecificityThis is a highly specific antibody against DERP6
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DERP6/C17orf81
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen BRCA1 is directly involved in DNA repair, DERP6 is thought to be involved in p53-mediated transcriptional regulation, Expressed ubiquitously with highest expression in liver, Like p53, Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome, The gene encoding DERP6 maps to human chromosome 17, Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death, Two key tumor suppressor genes are associated with chromosome 17, brain and skeletal muscle, colon, heart, is a 316 amino acid protein that localizes to the cytoplasm and exists as multiple alternatively spliced isoforms, namely, p53 and BRCA1, prostate gland and fallopian tubes, testis, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, which comprises over 2, 200 genes, 5% of the human genome and encodes over 1, DERP6
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names DERP6, Dermal papilla derived protein 6, ELP5_HUMAN, HSPC002, MSTP071, S phase 2 protein, chromosome 17 open reading frame 81, dermal papilla-derived protein 6, MST071
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetDERP6
Short nameDERP6 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameDERP6 (Antibody to)
Alternative techniqueantibodies
Identity 30617
Gene ELP5
Long gene name elongator acetyltransferase complex subunit 5
Synonyms gene C17orf81
Synonyms gene name chromosome 17 open reading frame 81
Synonyms DERP6
Synonyms name dermal papilla derived protein 6 S-phase 2 protein
Locus 17p13, 1
Discovery year 2006-02-13
GenBank acession BC002762
Entrez gene record 23587
Pubmed identfication 22854966
RefSeq identity NM_015362
Classification Elongator acetyltransferase complex
Havana BLAST/BLAT OTTHUMG00000177974

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